1,3-Dipolar cycloaddition reactions of N-metliyl-C-substituted phenylnitrones with N-methylmaleimide were studied. The reaction of p-dimethylamino and 4-benzyloxy-3methoxy substituted phenylnitrones with N-methyl maleimide gave only cis cycloadducts. Contrarily, the reaction of p-nitro and p-chloro substituted phenylnitrones with Nmethylmaleimide gave cis and trans cycloadducts.The substituent effects on the stereochemistry of N-methyl-C-substituted phenylnitrone cycloaddition reactions are discussed.
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