The disposal of culture media containing antibiotics is a daily practice in research laboratories at any level (ie, academia, industry, federal/state). Generally, good microbiological practices recommend that the biohazard be treated before disposal of the culture media. This brief summary aims to provide a different angle in the waste management of culture media containing antibiotics from the perspective of handling the biohazard (microbiological agent) and the chemical hazard (antibiotic) before disposal. Available practices and suggested discussion points are presented to initiate conversation among biosafety professionals and within institutions.
Institutional health and safety programs are responsible for minimizing personnel risk in working with animals that have been administered hazardous chemicals. Regulations and associated guidance are lacking in specific processes for managing these animals. A chemical control banding system categorizes chemicals into bands where each band level is associated with specific control practices. This article describes a general approach to the engineering, administrative, and personal protective equipment practices for developing an animal chemical control banding system. An internal committee should be responsible for conducting the risk assessments to assign chemicals used in animals into band levels, with many factors and resources included to facilitate in this process. The authors provide examples from their home institution where an animal chemical banding system was implemented. Institutions can use this information when designing their own programs, which will likely be unique in consideration of their specific needs and resources.
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