Background and Aims-Although the zinc finger transcription factor GATA4 has been implicated in regulating jejunal gene expression, the contribution of GATA4 in controlling jejunal physiology has not been addressed.

This paper provides evidence of an education-health relationship among older adults, even after controlling for individual and family background characteristics. It also explores to what extent this relationship represents an independent effect of education on health. An identification strategy using the quarter of birth and a set of parental and sibling characteristics as instrumental variables for education is used to purge estimates of biases resulting from error components correlated with education. The results suggest that the previously observed correlation between educational attainment and adult health has a causal component.

We present 42 rapidly evolving (time spent above half-maximum brightness t 1/2 12 d) extragalactic transients from Phase I of the Zwicky Transient Facility (ZTF), of which 22 have spectroscopic classifications. This is one of the largest systematically selected samples of day-timescale transients todate, and the first with spectroscopic classifications. Most can be classified as core-collapse supernovae (SNe), and we identify several predominant subtypes: (1) subluminous Type IIb or Type Ib SNe; (2) luminous Type Ibn or hybrid IIn/Ibn SNe; and (3) radio-loud, short-duration luminous events similar

Background Self-management of complex medication regimens for chronic illness is challenging for many older adults. Objectives The purpose of this study was to evaluate health status outcomes of frail older adults receiving a home-based support program that emphasized self-management of medications using both care coordination and technology. Design Randomized controlled trial with three arms and longitudinal outcome measurement. Setting Older adults having difficulty self-managing medications (N = 414) were recruited at discharge from three Medicare-certified home health care agencies in a Midwestern urban area. Methods All participants received baseline pharmacy screens. The control group received no further intervention. A team of advanced practice nurses and registered nurses coordinated care for 12 months to two intervention groups who also received either an MD.2 medication-dispensing machine or a medplanner. Health status outcomes (Geriatric Depression Scale, Mini-Mental Status Examination, Physical Performance Test, and the SF-36 Physical Component Summary and Mental Component Summary) were measured at baseline, 3, 6, 9, and 12 months. Results After covariate and baseline health status adjustment, time by group interactions for the MD.2 and medplanner groups on health status outcomes were not significant; time by group interactions were significant for medplanner and control group comparisons. Discussion Participants with care coordination had significantly better health status outcomes over time than those in the control group, but addition of the MD.2 machine to nurse care coordination did not result in better health status outcomes.