To examine basic COVID-19 knowledge, coping style and exercise behavior among the public including government-provided medical cloud system treatment app based on the internet during the outbreak. Besides, to provide references for developing targeted strategies and measures on prevention and control of COVID-19. We conducted an online survey from 11th to 15th March 2020 via WeChat App using a designed questionnaire. As well as aim to diagnose COVID-19 earlier and to improve its treatment by applying medical technology, the “COVID-19 Intelligent Diagnosis and Treatment Assistant Program (nCapp)” based on the Internet of Things. Valid information was collected from 1893 responders (47.07% males and 52.93% females aged 18–80 years, with a mean age of 31.05 ± 9.86) in 20 provincial-level regions across China. From the responders, 92.90% and 34.81% were scaled pass and good and above scores for the knowledge about the novel coronavirus epidemic. 38.44% were scaled poor scores and only 5.40% were scaled good and above scores for appropriate behavior coping with the pandemic. Among the responders, 52.14% reported having active physical exercise in various places during the previous 1 week. For all the responders, appropriate behavior coping correlated positively with physical exercise ( p < 0.05); the daily consumed time for getting the epidemic-related information correlated positively with the score for cognition on the epidemic’s prevention measures ( r = 0.111, p < 0.01) and on general knowledge about the epidemic ( r = 0.087, p < 0.01). Targeted and multiple measures for guidance on the control of COVID-19 among the public should be promoted to improve the cognition on basic knowledge, behaviors and treatment.
Highlights
CircANKIB1 was upregulated in OS tissues and cells.
CircANKIB1 downregulation suppressed the progression of OS by upregulating miR-217.
MiR-217 exerted its anti-cancer roles in OS cells via targeting PAX3.
CircANKIB1 modulated PAX3 expression through sponging miR-217.
Background
Chondrosarcomas is a rare tumour that has a variable biological characteristic. Also, their treatment clinically and surgically is controversial. We performed a comparison review of different regional institutions series with the aim of assessing the clinical outcome of patients.
Purposes
We, therefore, compare different institutions from different regions patients with grade 1 to 3 chondrosarcomas to (1)determine difference in survival rate, (2) local recurrence results, (3) determine successful outcome after surgery, (4) differences among surgical procedures. (5) Determine any association of clinical and demographic behaviour with gender, follow-up, treatment and chondrosarcoma affected body locations.
Methods
A retrospective review of 33 chondrosarcoma(all grades) patient’s data since 2013, compared with 15 author’s total 868 patients research literature to find more about clinical and statistical advantages and similarities with our study. Here is mentioning of clinical information’s, surgery type categorised, adjuvants types, genders, follow-up years, recurrence, affected areas, death rates, successful outcome and survival rates by using statistical methods.
Results
The overall survival rate was 94%, successful outcome 85% in 4.3 + 1.2 years follow-up. Observed wide resection, distilled water as adjuvant, chemo & radiotherapy significantly shows excellent result over our compared chondrosarcoma literature datas. We have also marked that females and humerus bone are more affected by chondrosarcoma among those literatures data.
Conclusions
Low-grade chondrosarcoma of the skeleton can be treated with wide resection and by the use of distilled water, which give good oncological outcome and a very low rate of post-surgical complications, as well as chondrosarcoma all grades recurrence.
Background Oral antibiotics are used to treat asymptomatic bacteriuria during the perioperative period of joint replacement usually. However, there is no unified conclusion on whether or not asymptomatic bacteriuria causes infection around joint prostheses, and the efficacy of antibiotics is unknown. Methods We systematically searched PubMed, CNKI, Ovid, Cochrane Library, EMBASE, manual research, and references of relevant articles up to January 1, 2020, to identify observational studies comparing. The Cochrane systematic review method was used, and the review Manager 5.3 software was used for analysis. Result (1) Nine articles were enrolled, involving 29844 cases of joint arthroplasty, including 2366 cases of asymptomatic bacteriuria. (2) The periprosthetic joint infection had a significantly higher incidence in the asymptomatic bacteriuria group than that in the non-asymptomatic bacteriuria group (Odd Ratio: OR=3.15, 95%CI: 1.23-8.02, P=0.02). (3) Seven in the nine articles reported the use of antibiotics for treating perioperative asymptomatic bacteriuria, and there was no significant difference in the incidence of Periprosthetic joint infection between two groups (OR=1.64, 95%CI: 0.84-3.23, P=0.15). Conclusion The occurrence of asymptomatic bacteriuria in the perioperative period of joint arthroplasty is a risk factor for periprosthetic joint infection, and the use of antibiotics for asymptomatic bacteriuria does not change the incidence.
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