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ÖZET Amaç: Bu çalışmada bir genel yoğun bakım ünitesinde (YBÜ) izlenen travma hastalarının genel özellikleri incelenmiş, bu hastalardaki mortalite oranı ve mortaliteye etki eden faktörler saptanmaya çalışılmıştır. Gereç ve Yöntem: Konya Numune Hastanesi'nde Ocak 2012-Mart 2013 tarihleri arasında genel YBÜ'de takip edilen 108 travma hastasının verileri retrospektif olarak incelendi. Hastaların demografik özellikleri ve klinik verileri kaydedildi. Hastalar YBÜ sonuçlarına göre sağ kalanlar ve ölen hastalar olarak iki gruba ayrıldı. Mortalite oranı ve bu orana etki eden faktörler incelendi. Bulgular: Çalışmaya 108 travma hastası dahil edildi. Mortalite oranı %19,4 tespit edildi. Hastaların median yaşları 44,5 ve %75,9'u erkek olarak tespit edildi. Medyan Glasgow Koma Skorları ölüm grubunda sağkalım grubuna göre daha düşük (5 (3-8) vs. 15 (13-15), p<0,0001), medyan APACHE II skorları daha yüksek (20 (15-26) vs. 10 (8-13), p<0,0001) ve median yatış süreleri daha uzun (27 (5-62,5) vs. 2 (1-5), p<0,0001) tespit edildi. En sık görülen travma etiyolojisi %47,2 oranda trafik kazası olup, hastaların %52,7'sinde kafa travması mevcut idi. Herhangi bir nedenle vücudunda fraktür bulunan hastaların oranı sağ kalan hasta grubunda daha yüksek bulundu (%66,7 vs. %33,3, p=0,007). Hastaların %38,9 eritrosit süspansiyonu, %27,8'i taze donmuş plazma, %0,9'u trombosit süspansiyonu ve %8,3'ü albümin almıştır. İnvaziv mekanik ventilasyon, %27,8 oranda yapılmış olup, median İMV süresi 5 (1,75-33,5) gün tespit edildi. Hastaların %42,6'sı opere edilmiştir. Trakeostomi, renal replasman tedavisi, bronkoskopi ve perkütan endoskopik gastrostomi uygulanan hastaların oranı ölen hasta grubunda daha yüksek tespit edildi. Logistic regresyon analizinde ileri yaş (p=0,016, OR: 1,054; %95 CI: 1,010-1100) ve düşük Glasgow Koma Skoru (p<0,0001, OR: 0,583; %95 CI: 0,456-0,745) yoğun bakımdaki travma hastalarının mortalitesini etkileyen bağımsız risk faktörleri olarak bulundu. Sonuç: YBÜ'de travma hastalarının mortalitesini etkileyen bu faktörlerin belirlenmesi ile ülkemizdeki diğer yoğun bakımlarda travma hastalarının yönetimine olumlu katkıda bulunabileceğimizi düşünmekteyiz. Anahtar Kelimeler: Yoğun bakım ünitesi, mortalite, travma SUMMARY Objective: The aim of this study was to determine the mortality rate and factors affecting the mortality of trauma patients in general intensive care unit (ICU) of a state hospital. Material and Method: Data of trauma patients hospitalized between January 2012 and March 2013 in ICU of Konya Numune Hospital were retrospectively analyzed. Demographic characteristics and clinical data of patients were recorded. Patients were divided into two groups as survivors and dead. Mortality rate and factors affectin mortality were examined. Results: A total of 108 trauma patients were included in the study. The mortality rate of overall group was 19.4%. Median age of the patients was 44.5 years and 75.9% of them were males. Median Glasgow Coma Scale of death group was lower (5 (3-8) vs. 15 (13-15), p<0.0001), median APACHE II score...

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Materials and methods: A total of 51 American Society of Anaesthesiologists (ASA) classification I-II patients aged 18-70 years who were scheduled to undergo elective anterior cruciate ligament reconstruction were included in the study. Patients were randomized into groups P, A, and C. Patients in group P (n = 16), received 150 mg of preoperative oral pregabalin, patients in group A (n = 17) received postoperative adductor canal blockade, and patients in group C (n = 18) received neither adductor canal block nor pregabalin. Surgeries were performed under spinal anaesthesia with hyperbaric bupivacaine following monitorization. Demographic data along with block features, hemodynamic data, mean opioid consumption, numerical rating scale score, White's fast-track score, and postoperative adverse effects were recorded. Results: Fifty-seven patients were enrolled in the study, and 6 patients were excluded from the study; the data of 51 patients were included in the final analyses. Demographic characteristics and hemodynamic data were similar between the 3groups. Postoperative opioid consumption was significantly lower in groups A and P compared with group C (group P = 178.75 mg, group C = 318.61 mg, group A = 236.47 mg; P < 0.05). The regression of sensory block was significantly slower in group P (P < 0.05). The first analgesic requirement was earlier in group C than in groups P and A (P < 0.05). Patients in group P had higher fast-track scores at 8 h and 12 h compared with group C (P < 0.05); however, group A fast-track scores were similar to those of the other 2groups (P > 0.05). The rate of postoperative adverse effects was similar between the groups (P > 0.05). Conclusion: Preoperative pregabalin (150 mg) reduced postoperative opioid consumption as much as adductor canal block in patients undergoing anterior cruciate ligament reconstruction. The first analgesic requirement was earlier in group C than in groups P and A. In addition, pregabalin can prolong the duration of spinal sensory block and shorten the time required to achieve high fast-tracking scores. We recommend the use of both methods as a part of multimodal analgesia.

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