352 1 rere. Grade; endlich wurde fie bleibend negativ bis ziini giinzliclien Voriibergange der Wollte. Diefe letztcreri Verfiiclie zeigen dafs der Galvanometer bei Unterfuchungen iiber die atmofpl~tirifche Elektricitat lellr niitzlicli werden kann. Wemi es er\viefen ware, dafs die Ehktricitst ziir Eildnng des Hagels beitrsst, fa wiirde diefs Infirament das einzige feyn welclies die Menge von Elektricitat anf eiiie genaue Art keniien lelirte, die von melir oder wenigcr ziigel'charften und erhabenen , oder m e h r oder weniger niit derp Bodeii verbundeneii Spitaen eingefogen wird., VI. jPuszug aus einer Abiiandlung uBer die Bagae-. tiJ;rung ; yon Hrn. SAVARY. (Gelefen In der Akad. der WiIienfchaften zu Paris am 31. Jul. 1826. Aus Ferr. d. Bullet. Sciences rnathe'm. etc. Sept. 1826. p. 202.) M a n verdankt IIrn. A r a 6 o die WjClltige Beobnclitung , dars leitendo Dralite, Onrch welchc der Strom einer Volta'fcllen Saule oder eine Entladung von gew6linlicher Elektricitat Iiindurcligelit, den S l a l i l magnetifch rnachen. Die im leizteren Falle bewirlite +LagnetiGrung ilt nacli Hrn. Arago's AngaLe ein MI^ einfaches u n d f'ehr genaues Mittel, die Leitiingsfd,igkeit verfchiedener Iidrper fur die Elektricitat von 110h e n Spannungen zii beliimmen. Das Gnnreiclie Verfahren, 'was derf'elbe fiir diere Art von IKelTiing erdadit bat, belieht darin: 1) d a 6 er einen elekiril'cheri Grad erreicht ; rin Erfiirderniis, dem Hrti. Davy's h!et:.tjde f:eilicli aucb nichr iri aller Strrnge gi.i;i:geu mag. i'.
Lymphocytes comprise up to 30% of the cells present in human bronchoalveolar lavage fluid and thus could participate in host response to infectious Aspergillus fumigatus conidia. We have examined the possibility that lymphocytes might play a role during early infection by either damaging the fungus or interfering with adherence. When incubated with A. fumigatus conidia for 20 h, highly purified 5‐day‐old lymphocytes activated with either IL‐2 or phytohaemagglutinin, but not untreated lymphocytes, were consistently able to reduce residual fungal biomass as estimated by a metabolic assay. T lymphocytes, but not NK cells, appeared to be responsible for this activity. Lymphocytes bound both A. fumigatus conidia and hyphae, and the antifungal activity of the lymphocytes required direct lymphocyte–fungus contact. In a separate set of experiments using release of 51Cr from 51Cr‐loaded fungi as an estimate of fungal damage, lymphocyte‐induced loss of fungal biomass was found to be due to loss of fungal adherence rather than to direct fungal damage. The detached hyphae were also found to be metabolically intact and to have normal morphology by electron microscopy. These data demonstrate that IL‐2‐ and phytohaemagglutinin‐activated lymphocytes exhibit a contact‐dependent ability to reduce adherence of germinating conidia of A. fumigatus to a surface.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.