Background: Oral Cancer Is One Of The World's Most Common Types Of Cancer, With Delayed Diagnosis And Poor Prognosis. IndiaIs Among The Leading Countries With A High Rate Of Oral Cancer Due To Its Increased Tobacco Use Rate.Aim: This Study Aims To Assess The Prevalence Of Oral Cancer Among Tobacco And Non-Tobacco Users In Tamil Nadu.Materials And Method: A Systematic Review Of Cross-Sectional Studies Were Performed. The Data Was Searched Using ElectronicDatabases, And 376 Articles Were Screened. The Intervention And Outcomes Were Assessed In The Studies Included In TheSystematic Review. The Bias Assessment Done For The Article Was Based On The Newcastle-Ottawa Scale.Results: Overall Analysis Of The Studies Shows That The Prevalence Of Oral Cancer In Tamil Nadu Has Been Significantly IncreasingAnd That Smokeless Tobacco Causes Oral Cancer Compared With Other Forms Of Tobacco.Conclusion: The Prevalence Of Oral Cancer In Tamil Nadu Is Increasing Significantly With The Usage Of The Increased Amount OfTobacco, And Awareness Of The Ill Effects Of Tobacco Usage May Considerably Decrease The Rates.
Class II mandibular furcation defect is a periodontal condition characterized by a cul-de-sac lesion, a definite parallel constituent with only a portion of alveolar bone remaining intact. There may be involvement of vertical bone loss. Local drug deliveries such as Boric acid, alendronate gel, and other drugs exhibited anti-inflammatory, antibacterial & osteoblastic differentiation activity. The present systematic review compares the drugs based on their outcomes and pharmacological action. To analzse & compare various forms of local drug delivery systems on a class II furcation. A search was conducted using PubMed, Google scholar, science direct, and Pub Med central using MeSH terms – local drug delivery in periodontics, boric acid in the management of class II mandibular furcation, simvastatin in the treatment of furcation. A total of 560 articles were screened; 58 out of 560 were full-text articles accessed for eligibility, and five articles were included in the systematic review. PRISMA guidelines were used for reporting this review. In addition, five randomized controlled trials were enclosed and used in this systematic review. The various local drugs used in treating class II mandibular furcation defects are effective in the prevention of bleeding on probing, bone resorption, gingival bleeding index and increase in the bone fill, and microbial deposit removal. The managing of class II mandibular furcation defect with the drugs mentioned in this review can be effective by reducing several clinical parameters such as bleeding on probing, gingival indices, osteoblastic differentiation, bone fill, etc., Considering the results of the studies, it can be concluded that it can be used as a therapeutic therapy against class II furcation defects with positive outcomes.
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