Background:Matrix metalloproteinase (MMP) are involved in bone transformation at the extraction site postdental extraction. We examined the genetic association between single nucleotide polymorphisms of MMP-1 and continuous atrophy of edentulous mandible.Methods:Buccal cells from 33 edentulous patients were collected using sterile wooden spatula and were suspended in 15 ml falcon tubes containing 1.5 ml of cell lysis buffer, without proteinase K. The cells were transported to the laboratory on ice and were stored at −20°C until being processed.Results:Of the samples analyzed, 26 edentulous patients (78.8%) carried 2G allele, while 7 of them (21.2%) carried 1G allele.Conclusion:The patients with the alveolar bone resorption exhibited more of 2G allele while only 21.2% of them showed 1G allele, associated with excessive atrophy of edentulous mandible. This study may provide genetic background to identify susceptible individuals prone to develop jawbone atrophy after dental extraction.
Background:
Guided Endodontics is suggested as a reliable method for management of teeth with pulp canal obliteration (PCO). The guide used for this usually involves multiple teeth to gain stability but is bulky. It is therefore suboptimal to be used along with rubber dam.
Aim:
To describe the use of a minimized single-tooth guide template in three patients with radiographic evidence of PCO.
Design:
The template was designed and fabricated using the cone-beam computed tomography (CBCT) scan and a surface scan image of the involved teeth. In all three patients, the root canals were successfully negotiated within 15 minutes, with the template involving only the tooth in focus or with neighboring half of the teeth. The operator stabilized the template if required.
Conclusions:
This case series shows clinically that successful outcome can be obtained during guided endodontics with the use of a single-tooth template in previously traumatized anterior teeth with PCO.
Background and Aim:
Complete removal of gutta-percha and sealer is an important step during retreatment. The aim of this study was to assess the efficacy and time taken by full counterclockwise rotary motion of a reciprocating file in the removal of gutta-percha and BioRoot™ RCS bioceramic sealer.
Materials and Methods:
Thirty-six extracted human mandibular premolars were instrumented with Mtwo rotary files and obturated using lateral condensation technique with gutta-percha and BioRoot™ RCS bioceramic sealer. The teeth were divided into three retreatment groups (
n
= 12) based on the kinematics used: Group I, Mtwo retreatment (Mtwo-R) files; Group II, Reciproc files used in reciprocation mode (Reciproc-R); and Group III, Reciproc files used in full counterclockwise motion (Reciproc-CCW). The efficacy of gutta-percha and bioceramic sealer removal was assessed by volume of gutta-percha removed using cone-beam computed tomography and area of remaining gutta-percha and bioceramic sealer using ImageJ software after longitudinal sectioning. Statistical analysis was done by one-way analysis of variance test and Tukey's multiple
post hoc
tests.
Results:
Reciproc-CCW motion was significantly efficient in the removal of gutta-percha and bioceramic sealer in comparison to Mtwo-R files and Reciproc-R. The time taken for gutta-percha and sealer removal was least for Reciproc-R (325.5 ± 101.68 seconds) and was statistically significant in comparison to the other groups.
Conclusion:
Within the limitations of the study, Reciproc-CCW was an effective method of removal of gutta-percha and bioceramic sealer during retreatment.
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