Background:
The need for accurate and timely detection of Intracranial hemorrhage (ICH) is utmost important to avoid untoward incidents that may even lead to death.Hence, this presented work leverages the ability of a pretrained deep convolutional neural network (CNN) for the detection of ICH in computed tomography (CT) brain images.
Methods:
Different frameworks have been analyzed for their effectiveness for the classification of CT brain images into hemorrhage or non-hemorrhage conditions. All these frameworks were investigated on CQ500 dataset. Furthermore, an exclusive preprocessing pipeline was designed for both normal and ICH CT images. Firstly, a framework involving the pretrained deep CNN, AlexNet, has been exploited for both feature extraction and classification using the transfer learning method, secondly, a modified AlexNet-Support vector machine (SVM) classifier is explored and finally, a feature selection method, Principal Component Analysis (PCA) has been introduced in the AlexNet-SVM classifier model and its efficacy is explored.These models were trained and tested on two different sets of CT images, one containing the original images without preprocessing and another set consisting of preprocessed images.
Results:
The modified AlexNet-SVM classifier has shown an improved performance in comparison to the other investigated frameworks and has achieved a classification accuracy of 99.86%, sensitivity and specificity of 0.9986 for the detection of ICH in brain CT images.
Conclusion:
This research has given an overview of a simple and efficient framework for the classification of hemorrhage and non-hemorrhage images. Also, the proposed simplified deep learning framework manifests its ability as a screening tool to assist the radiological trainees for the accurate detection of ICH.
Our firmware promises to be an excellent training tool for organ anastomosis. Considering the complexity and likely complications of MAPS, it is a sine qua non that the surgeon be highly experienced and skilled. Surgical simulation is attractive because it avoids the use of patients for skills practice and provides relevant technical training for trainees before they can safely operate on humans.
The application of pulsed electric field is emerging as a new technique for cancer therapy. The irreversible electroporation is the major bioelectric effect to induce cell death. The pulsed electric field is transferred to target deep tissue non-invasively and precisely when the pulse duration is in picosecond regime. In this proposed work, the intense electric field with 100 ps pulse width is used for irreversible electroporation. If the electric field strength increases, the pore in the cell membrane enlarges, causing a loss of membrane intactness and the direct killing of cancer cells. This phenomenon is explored by molecular dynamics simulation. The electric field in the range of 0.8-5 V/nm is used for membrane dynamics. The membrane deformation occurs at the electric field of 5 V/nm. Picosecond pulsed electric field has a wealth of ultra-band spectrum, with extended time and enhanced spatial resolution and low signal distortion. The ultra-wide band antenna is used as a pulse delivery system for non-invasive skin cancer therapy.
Cancer therapy is one of the several new applications which use nanosecond and subnanosecond high voltage pulses. New treatment based on electromagnetic (EM) fields have been developed as non-surgical and minimally invasive treatments of tumors. In particular, subnanosecond pulses can introduce important non-thermal changes in cell biology, especially the permeabilization of the cell membrane. The motivation behind this work is to launch intense subnanosecond pulses to the target (tumors) non-invasively. This works focuses on the design of a compact intense pulsed EM radiating antenna. In tense EM waves radiated at the first focal point of the Prolate Spheroidal Reflector (PSR) are focused at the second focal point where the target (tumor) is present. Two antennas with PSR but fed with different compact wave radiator are designed to focus pulsed field at the second focal point. The PSR with modified bicone antenna feed and PSR with elliptically tapered horn antenna feed are designed. The design parameters and radiation performance are discussed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.