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Bolus injection of the nonionic iopromide does not statistically significantly affect infarction volume or cerebral ischemia symptoms. Nonionic rather than ionic contrast agents should be preferred during acute cerebral ischemia.

Enantiomeric diastereomers can be selectively obtained from the fumarate 1 and dienes. For instance, the uncatalyzed Diels‐Alder reaction of 1 with cyclopentadiene gives preferentially the diastereomer 2a (2a : 2b = 98 :2); with TiCl4 as catalyst, on the other hand, 2b is the main product (2a : 2b = 5 :95). Analogous results were obtained for less reactive dienes [R*OH = (S)‐ethyl lactate].

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