Objective To observe the role of uterine artery Doppler flow velocimetry at midtrimester in prediction of preeclampsia. Method 179 women carrying \16 weeks of pregnancy, with singleton fetus and without any fetal anomaly were recruited and were divided in high-risk and low-risk group. Doppler velocimetry of uterine artery was done at 24-26 weeks. Any notch in uterine artery, unilateral or bilateral, or RI [ 0.6, was considered abnormal. Women were followed up and development of preeclampsia noted. Result Sensitivity and specificity of abnormal uterine artery Doppler study for prediction of preeclampsia were 73.33 and 86.48 % in high-risk and 57.14 and 95.83 % in low-risk group, respectively. Relative risk with 95 % confidence interval was 5.427 (2.272-12.958) in high-risk and 13.65 (5.669-32.865) in low-risk women. Conclusion Doppler velocimetry of uterine artery at 24 weeks can be used as a reliable screening test for prediction of preeclampsia in both high-risk and low-risk women.Keywords Doppler velocimetry of uterine artery Á Preeclampsia Á Screening test Á High-risk and low-risk women

No abstract

INTRODUCTIONSafe and legal abortion is considered to be a key intervention for improving women's health and quality of life.1 In our country a significant number of women practice contraception but Medical Termination of Pregnancy (MTP) is also used to control family size and birth spacing.2 As a result, an overwhelming proportion of induced abortions (6.7 million annually-an indirect estimate) take place in India 3 and elective termination of pregnancy is considered as a commonly performed gyanecological procedure. 4 Second trimester abortions constitute 10-15% of all induced abortions worldwide, but are related to twothirds of major abortion related complications.5 During the last decade, medical methods for second trimester induced abortions have has considerably improved and became safe and more accessible.Although several methods have been tried over the years with varying success, the ideal method for mid-trimester abortion remains elusive, as indicated by the constant search for new methods. [5][6][7][8][9] Ethacridine lactate has a long history of use in our country and is recommended for use ABSTRACTBackground: Second trimester abortions generally account for less number of patients as compared to first trimester abortions as patients generally come earlier as soon as pregnancy is recognized but now days due to advent of USG many cases of fetal anomaly are detected earlier accounting for increasing number of cases of second trimester. Methods: Present study was conducted among patients with pregnancy between 13-20 weeks of period of gestation (to be randomly assigned) after getting approval from institutional ethics committee and informed consent from the patient. Participants were randomly allocated to receive 400 µg of misoprostol either sublingually or intravaginally every six hours for a maximum of 5 doses. The blood pressure, pulse rate & temperature and side effects monitored every 3 hrs. If women in either group failed to abort after 48 hours of initiation of treatment termed as failure. In cases of failure they were given additional doses of sublingual misoprostol till abortion occurred. Primary outcome variable compared was success rate at 48 hours. Secondary outcome variables compared were bleeding patterns, completeness of abortion, induction abortion interval and any side effects. Results: It has been found that vaginal misoprostol 400 micro gm achieved a success rate to 100% in 48 hours, while the success rate was 93.33% with the sublingual route. (P = 0.4915, NS). Conclusions: Thus from our limited study population, we conclude that there is no significant difference in efficacy and complications between the two routes, although a larger cohort is required to get more dependable result.

No abstract