Most authorities suggest Sydenham chorea (SC) to be an autoimmune disease that is triggered by a streptococcus infection, subsequently resulting in a hypersensitivity humoral reaction to the infection and cross-reactivity streptococci antigens and human tissue antigens through antigen mimicry. Typically, the first episode occurs 6 to 8 weeks after an episode of GABHS pharyngitis. Diagnostic evaluation of Sydenham chorea should include a careful history and neurologic examination. This case presents an 11-year old girl with a primary complain of involuntary movements, slurred speech and an unstable gait since 1.5 month. Chorea is a clinical diagnosis, made after a careful assessment to exclude other causes. It is important to consider whether a child presenting with chorea could have an autoimmune disorder. Laboratory investigations and echocardiography may be indicated, particularly if there are no other features to support a diagnosis of rheumatic fever.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.