Cardiovascular disease (CVD) is a collective group of diseases that affect the functioning of heart and blood vessels. Coronary artery bypass grafting (CABG) is considered an effective treatment and is commonly used worldwide for patients with Coronary artery disease (CAD). As there is substantial decline in operative mortality with CABG over the past 30 years, quality of life (QOL) has become an important outcome to determine the benefits and risks associated with CABG. The aim is to assess the QOL in patients after CABG and also to determine the factors that are associated with of QOL after CABG. A Cross sectional study was carried out for a period of 9months among 100 CABG subjects whose postoperative period was minimum 6 months. Quality of life was assessed using the SF-36 questionnaire. The data collected were scored by RAND analysis and estimated by using SPSS. Of total 100 CABG subjects, the factor gender has its effects on physical functioning, emotional role, and general health. Based on the factor age, the domains vitality and physical role are improved more in patients <60 compared to patients >60 post-CABG. Quality of life is affected by CABG, especially the physical role, vitality, social functioning, and general health domains. Factors that are affecting the QOL following CABG are smoking, education, economic, marital status, and co-morbidities as measured by the SF-36 domains.
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