This study verified the factors affecting the antifungal efficacy of sanitizers against ochratoxin A-producing fungi. The fungi Penicillium nordicum, Penicillium verrucosum, and Aspergillus westerdijkiae were exposed to three sanitizers at three concentrations: peracetic acid (0.3, 0.6, 1%), benzalkonium chloride (0.3, 1.2, 2%), and sodium hypochlorite (0.5, 0.75, 1%) at three exposure times (10, 15, and 20 min), three temperatures (10, 25, and 40 °C), and with the presence of organic matter simulating clean (0.3%) and dirty (3%) environments. All the tested conditions influenced the antifungal action of the tested sanitizers. Peracetic acid and benzalkonium chloride were the most effective sanitizers, and sodium hypochlorite was ineffective according to the parameters evaluated. The amount of organic matter reduced the antifungal ability of all sanitizers. The longer exposure time was more effective for inactivating fungi. The temperature acted differently for benzalkonium chloride, which tended to be favored at low temperatures, than for sodium hypochlorite and peracetic acid, which were more effective at higher temperatures. The knowledge of the parameters that influence the action of sanitizers on spoilage fungi is vital in decision-making related to sanitizing processes in the food industry.
The association between personality traits, life balance domains, and work addiction among entrepreneurs was investigated. Multiple regression and canonical correlation analysis of 106 participants indicate a significant relationship between personality traits, life balance domains, and work addiction. In particular, neuroticism was positively related to work addiction, as suggested in earlier studies. Among all the life balance domains five of the 10 life balance domains had a significant positive relationship with work addiction: positive orientation, substance use, sleep disturbance, stress/anxiety, and friendship. Results obtained from this study will help career and mental health counselors better understand entrepreneurs’ needs and life balance domains. By identifying neuroticism and stress levels among entrepreneurs, career counselors can better understand work addiction tendencies and use appropriate interventions accordingly.
Introduction:In Brazil, the medicines marketed for acute external otitis are ciprofloxacin and the combination polymyxin B, neomycin, and fluocinolone. The aim of this study was to evaluate the proportion of cure and cost-effectiveness of quinolone versus polymyxin B, neomycin, and steroid combined (PNS) for acute external otitis from the perspective of the Brazilian Public health system.Methods:A systematic review was conducted using Medline, Cochrane Library, CRD and Lilacs databases. Studies evaluating quinolones versus PNS in the treatment of acute external otitis were included. A cost-effectiveness model was made using a decision tree, considering the direct cost of treatment. Univariate sensitivity analysis was conducted, considering the confidence interval of clinical outcomes and a 15 percent variation in cost.Results:The proportion of cure in up to 10 days was 70.1 percent with quinolone and 60.4 percent with PNS (p = 0.004). The treatment costs were BRL 16.22 (USD 5.02) with quinolone and BRL 3.04 (USD 0.94) with PNS. The incremental cost-effectiveness ratio was BRL 136.25 (USD 42.15) per cure in up to 10 days for quinolone in relation to PNS. This value was more sensitive to clinical outcomes, ranging from BRL 95.48 (USD 29.54) to BRL 254.25 (USD 78.65) for cure with quinolone and from BRL 90.77 (USD 28.08) to BRL 262.57 (USD 81.23) for cure with PNS. These values should be considered with caution because acute external otitis is resolved within a few days and treatment effectiveness is not measured by life years.Conclusions:There are few studies on therapeutic alternatives available in Brazil. Through the available evidence, there is a lack of results on the effects attributed to each drug. Considering the higher effectiveness, low cost and rational use of antibiotics, quinolone is considered a cost-effective alternative for acute external otitis in Brazil.
dos Santos Silva 3 -UFPB RESUMO As oficinas mecânicas são estabelecimentos que apresentam alto potencial de contaminação. O objetivo deste artigo foi analisar o cenário do saneamento básico nas oficinas mecânicas no município de Campina Grande -PB. A análise de dados foi realizada através de uma pesquisa de campo acompanhada de consulta bibliográfica e documentos oficiais. No estudo foi possível verificar a contaminação de galerias de águas pluviais por meio do derramamento de resíduos de lubrificantes usados e a ausência de logística reversa em diversas oficinas. Os problemas apontados no trabalho evidenciam a necessidade de uma forma mais adequada de gerenciamento dos resíduos e servem de base para aplicação da legislação do plano nacional de saneamento básico (PNSB).
Objetivo: identificação da prevalência, características e motivos que levaram a puérpera a procurar o Pronto Atendimento e associação com o tipo de parto. Métodos: estudo quantitativo de delineamento transversal. Dados extraídos das informações constantes nas fichas de Pronto Atendimento em um hospital de ensino de mulheres que estavam vivenciando o período pós-parto. Utilizou-se instrumento próprio para a coleta de dados, analisados por estatística descritiva simples e teste qui-quadrado, utilizando o software Statistical Package for the Social Science. O projeto foi aprovado pelo Comitê de Ética em Pesquisa. Resultados: foram incluídos 89 registros de puérperas que procuraram o Pronto Atendimento, correspondendo à prevalência de 16%. Das 89 mulheres, 60,6% tinham realizado cesárea. Os principais motivos que levaram à procura por Pronto Atendimento foram: alterações na ferida operatória (55%) e sangramento vaginal aumentado (20,2%). Houve associação entre maior procura por Pronto Atendimento no período puerperal entre mulheres que tiveram parto cesáreo. Conclusão: a prevalência de procura por Pronto Atendimento na amostra do estudo foi de 16%, sendo o principal motivo as alterações da ferida operatória.
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