Citation for published item:orterD FtF nd elyD hF nd uzukiD uF nd qr¤ okeD hFF @PHIQA 9ypening of trnsEngen mrine orridor during the irly turssi X insights from osmium isotopes ross the inemurin!lienshin qD oin rood9s fyD uF9D leogeogrphyD pleolimtologyD pleoeologyFD QUS F ppF SHESVF Further information on publisher's website: Use policyThe full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that:• a full bibliographic reference is made to the original source • a link is made to the metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders.Please consult the full DRO policy for further details.

The full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that:• a full bibliographic reference is made to the original source • a link is made to the metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders.Please consult the full DRO policy for further details. .5 ‰, and predominantly have Ni isotopic compositions that are heavier than those of abiotic terrestrial and extraterrestrial samples extraterrestrial and abiotic terrestrial samples (-0.1 ‰ and 0.4 ‰)(0.15 ‰ and 0.27 ‰), and in some cases present-day seawater (1.44 ‰) and dissolved Ni from riverine input (0.80 ‰). In addition, the observed degree of isotopic fractionation in the marine sediments is far greater than that of these other sample matrices. However, a strong similarity is exhibited between the δ60Ni values of the organic-rich sediments studied here and those of ferromanganese crusts (0.9 to 2.5 ‰), suggesting that factors ubiquitous to the marine environment are likely to play a key role in the heightened level of isotopic fractionation in these sample matrices. A lack of correlation between the Ni stable isotope compositions of the organic-rich sediments and Ni abundance, suggests that isotopic fractionation in these sediments is not controlled by uptake incorporation or enrichment of Ni during sediment accumulation. Further, no relationship is observed between δ60Ni and TOC concentrations or bottom-water redox conditions, indicating that the organic carbon reservoir and levels of oxygenation at the sediment-water interface do not exert a primary control on Ni isotope fractionation in marine sediments. Following examination of these relationships, it is therefore more likely that the heavy Ni isotope compositions of marine sediments are controlled by the weathering environment and the dominant sources of dissolved Ni into the global ocean reservoir.

Polyacrylamide gel electrophoresis in sodium dodecyl sulphate (SDS) followed by protein staining has shown that extracts from 11 different grass pollens contained proteins with similar molecular weights to that of the allergen R7 from rye grass (Lolium perenne) pollen extract (i.e. 29,000–31,000 daltons). Western blotting and detection with polyclonal (rabbit) antibodies raised against the purified R7 (Rye I) allergen indicated that these proteins were antigenically related and their allergenic properties were demonstrated by the binding of human IgE to immunoblots. The distribution of cross-reacting antigenic determinants was further investigated by immunoblotting with 2 mouse monoclonal antibodies, R7M1 and R7M2, produced with purified R7 as the initial immunogen. The 2 monoclonal antibodies were shown to react with ‘R7-like’ components of grass pollen extracts other than the component from rye grass. Differences in the distribution of R7M1 and R7M2 binding were found indicating that they are directed at separate R7 epitopes.

New Re-Os molybdenite geochronology is presented from the Ballachulish Igneous Complex (433.5 AE 1.8 Ma) and the Kilmelford Igneous Complex (425.8 AE 1.7 Ma) of the SW Scottish Highlands. The sulphide mineralization in the Ballachulish Igneous Complex is related to the latest phase of granite magmatism, and therefore the new Re-Os age provides a minimum crystallization age, c. 3.7 Ma earlier than previous crystallization age estimates. This Re-Os age overlaps U-Pb ages obtained from subduction-related granitic and appinitic magmatism north of the Great Glen Fault, and an origin related to active subduction rather than slab breakoff is proposed for the Ballachulish Igneous Complex. Molybdenite mineralization in the Kilmelford Igneous Complex is spatially and genetically associated with porphyry Cu mineralization, which is consistent with the rapid ascent of volatile-rich magma during early rebound following the breakoff of subducted oceanic lithosphere. The Kilmelford Igneous Complex and the coeval Lorn Lava Pile may represent the earliest of the igneous bodies predicted by slab breakoff, indicating that slab breakoff occurred at c. 426 Ma.

Deposition of black shale facies, one of the main contributors for hydrocarbon production, is commonly assumed to be linked to Oceanic Anoxic Events (OAEs), which are supposed to be generated during warm palaeoclimates. This assumption could bias the exploration for hydrocarbon source rocks preferentially towards sediments deposited under warm palaeonvironments, as a preferential guide for hydrocarbon exploration. As a consequence, the establishment of the links between palaeotemperature and the formation of organic-rich deposits is of primary importance. For this purpose, the Upper Sinemurian, Pliensbachian and Lower Toarcian (Lower Jurassic) deposits of the Asturian Basin in northern Spain, including more than 100 m thick succession containing organic-rich and black shale deposits, have been studied. Correlation between palaeoclimatic data, previously obtained from oxygen isotopes, and the TOC content reveals that black shales and organic-rich sediments were deposited not only during warming intervals but also during a prominent cooling event that occurred at the Late Pliensbachian. This cooling period has been pointed out as one of the main intervals to have developed ice caps in the poles during the Jurassic. On the contrary, no black shales were generated during the postulated Early Toarcian OAE, which coincides with a superwarming interval. Additionally, the study of the facies cycles and the measurement of gamma-ray in outcrops and its correlation with TOC content provides data on the use of natural radioactivity and sea level changes as a proxy for preliminary organic matter richness evaluation.Keywords: Organic-rich deposits, Climatic change, Oxygen isotopes, Carbon isotopes, Gamma ray, Sea level changes ResumenNormalmente se asume que la sedimentación de las facies de black shales, uno de los principales contribuyentes a la generación de hidrocarburos, está ligada a los Eventos Oceánicos Anóxicos (OAEs) y que éstas facies se formaron durante paleoclimas cálidos. Esta suposición puede orientar a la exploración de rocas madre de hidrocarburos preferentemente hacia los sedimentos depositados bajo paleoambientes cálidos. En consecuencia, el establecimiento de la relación entre paleotemperaturas y la formación de depósitos ricos en materia orgánica resulta de gran importancia para encontrar argumentos sobre este tema, aplicables a la exploración de hidrocarburos. Con este propósito se han estudiado los sedimentos del Sinemuriense Superior, Pliensbachiense y Toarciense Inferior (Jurásico Inferior) de la Cuenca de Asturiana, que incluyen más de 100 m de espesor de depósitos conteniendo facies con materia orgánica y black shales. La correlación entre los datos paleoclimáticos, obtenidos previamente a partir de isótopos de oxígeno, y el contenido de Carbono Orgánico Total (TOC) revela que los black shales y los sedimentos ricos en materia orgánica se depositaron no solo durante los intervalos cálidos sino también durante un destacado evento frío que se desarrolló durante el Pliensbachiense Superior. Est...

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Objectives: The global pandemic of coronavirus disease 2019 (Covid-19) may disproportionately affect persons in congregate settings, including those in residential substance use treatment facilities. To limit the spread of SARS-CoV-2 through congregate settings, universal testing may be necessary. We aimed to determine the point prevalence of SARS-CoV-2 in a residential treatment program setting and to understand the unique challenges of Covid-19 transmission in this setting. Methods: We performed a case series of SARS-CoV-2 rT-PCR testing via nasopharyngeal in a residential substance use treatment program for women in Boston. Staff and residents of the treatment program were tested for SARS-CoV-2. The primary outcome was SARS-CoV-2 test result. Results: A total of 31 residents and staff were tested. Twenty-seven percent (6/22) of the residents and 44% (4/9) of staff tested positive for SARS-CoV-2. All of the SARS-CoV-2 positive residents resided in the same residential unit. Two positive cases resided together with 2 negative cases in a 4-person room. Two other positive cases resided together in a 2-person room. One positive case resided with 2 negative cases in a 3-person room. One positive case resided with a negative case in a 2-person room. Based on test results, residents were cohorted by infection status and continued to participate in addiction treatment on-site. Conclusions: SARS-CoV-2 infection was common among staff and residents within a residential substance use treatment program for women in Boston. Universal SARS-CoV-2 testing in residential substance use programs can be instituted to reduce the risk of further transmission and continue addiction treatment programming when accompanied by adequate space, supplies, and staffing.

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