Objective: To determine the mortality rate in COVID-19 positive patients with acute kidney injury requiring hemodialysis. Study Design: Observational Retrospective study. Setting: Department of Nephrology, Patel Hospital, Karachi. Period: March, 2020 to May 2021. Material & Methods: Data was collected retrospectively from medical records of patients. Patients with positive COVID-19 PCR and having AKI requiring hemodialysis were included in the study. Data was collected by complete evaluation of COVID-19 patient records and their symptoms, clinical status and final outcome during their hospital stay was noted. Results: The frequency of acute kidney injury requiring hemodialysis in our tertiary care setup was found to be 12.2% (n=41). Amongst these there were 53.7% males (n=22) and 46.3% females (n=19) and the mean age of patients was found to be 64.82+ 11.2 years. The mean level of lymphocyte count was found to be 11.3 + 4.8 *109/L. The in hospital mortality of COVID-19 positive patients having AKI was documented to be 73.2% (n=30) as shown in Table-IV. The other group of patients included 11 patients who recovered from acute kidney injury after hemodialysis sessions and were discharged from the hospital. Conclusion: Since COVID-19 infection became pandemic in 2020 there still needs to be a lot of research done in different populations. Hospitalized patients with COVID-19 infection should be Screen for kidney impairment and provided proper treatment. There has been found a very close association between the severity of acute kidney injury and mortality among the critically ill patients.
Developments around new technology are opening new avenues for business, commerce, and management. From instantaneous, low-cost transaction processing, clearing, and settlement to the management of government & commercial banking ledgers, disruptive technologies like blockchain has numerous applications in financial engineering and innovative product development. Distributed ledger technology can be used to develop innovative Shariah-compliant products including financial instruments that are beneficial for the growth and development of the Islamic finance industry along with the achievement of Sustainable Development Goals (SDGs). In this paper, blockchain technology is proposed to develop Sukuk to finance development infrastructure projects in Pakistan. With adequate governance, innovative products along with legal and regulatory support, Islamic finance has the potential to make a reasonable contribution towards the development of infrastructure along with the rising standard of living for people, eventually supporting Sustainable Development Goals (SDGs) set by the United Nations General Assembly in 2015 for the year 2030. Rigorous infrastructure is the key to the successful implementation and achievement of Sustainable Development Goals (SDGs).
The biggest challenge for the Islamic banking industry in Pakistan is the scarcity of Shariahcompliant investment instruments and the absence of a lender of last resort (LOLR) facility for Islamic banks. Due to the problem of surplus liquidity, returns for Islamic banks in Pakistan are lower as compared to the conventional counterparts putting them at a competitive disadvantage with respect to their competitor conventional banks. Sukuk issuance is associated with a high cost of issuance and legal complexity, problems that could be solved by the application of blockchain technology. With the advent of cryptocurrency and developments around blockchain, technology experts, industry professionals along with Shariah scholars have been working to introduce FinTech in Shariah-compliant financing products and services. This research applies a qualitative approach. The study relies on primary data from interviews and secondary data from published sources, academic journals, government and private-sector reports, and public domain including newspaper articles, and websites. Interviews are conducted from blockchain technology experts along with banking & commerce industry professionals. This study highlights financial instability, lack of financial education and absence of political will being the main reasons for low Sukuk issuance in Pakistan. This study proposes a low-cost smart Sukuk structure to address the liquidity problem of the Islamic banking industry in Pakistan. It is found that smart Sukuk issuance and transaction fees are much lower than the current Sukuk issuances and are expected to be more secure and marketable internationally. Blockchain-based smart Sukuk are practicable to solve the problem of standardization and huge issuance and maintenance cost for the Sukuk industry. The proposed structure could be adopted by governments and organizations to issue Sukuk promising transparent, economical, efficient, and reliable business transactions for both parties.
Introduction: According to statistics till April, 2020 1,995,983 cases and 131,037 deaths have been reported globally with COVID-19 being a global threat posing great challenges to the healthcare system. Clinical data reviews and researchers have revealed that COVID-19 affects multiple organ especially liver, kidney and heart with primary damage to the respiratory system. Acute kidney injury and COVID-19 infection has been found to be linked to each other but the etiology remains unclear still. Method: This is an observational retrospective study conducted in nephrology department of Patel Hospital, Karachi. Data was collected retrospectively from medical records of patients. The study was carried out during the time period of March, 2020 till May 2021 for duration of 15 months. Patients with positive COVID-19 PCR and having AKI requiring hemodialysis were included in the study. Data was collected by complete evaluation of COVID-19 patient records and their symptoms, clinical status and final outcome during their hospital stay was noted. Results: The frequency of acute kidney injury requiring hemodialysis in our tertiary care setup was found to be 12.2% (n=41). Amongst these there were 53.7% males (n=22) and 46.3% females (n=19) and the mean age of patients was found to be 64.82+ 11.2 years. The mean level of lymphocyte count was found to be 11.3 + 4.8 *109/L. The in hospital mortality of COVID-19 positive patients having AKI was documented to be 73.2% (n=30) as shown in table-4. The other group of patients included 11 patients who recovered from acute kidney injury after hemodialysis sessions and were discharged from the hospital. Conclusion: Since COVID-19 infection became pandemic in 2020 there still needs to be a lot of research done in different populations. Hospitalized patients with COVID-19 infection should be Screen for kidney impairment and provided proper treatment. There has been found a very close association between the severity of acute kidney injury and mortality among the critically ill patients.
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