Enlarged facial pores are common cosmetic concerns that are attributed to multiple factors. Excess sebum production, decreased skin elasticity, and increased hair follicle volume are the three main causes of enlarged pores. Other factors include sex, aging, excessive sun exposure and improper use of cosmetic products. 1 Due to great psychological impact, people have been trying to find treatment for this problem. Many treatment options are available including isotretinoin, chemical peeling, and laser therapy. 2Microbotox has been proved to be effective in improving the sheen and texture of the skin, as well as decreasing sweat and sebum production and enlarged pores as it causes atrophy of sebaceous glands, which subsequently causes tightening of the skin envelope. 3 Microneedles (MNs) can create hundreds of reversible microchannels in non-invasive manner to enhance transdermal drug delivery and promote collagen production. 4 Depending on the previously mentioned data, this study aimed to compare the efficacy and longevity of intradermal microbotox
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