PurposeTo evaluate the outcome of cataract surgery in adult patients with uveitis.Materials and methodsIn this retrospective cohort study, medical charts of patients with uveitis and matched control patients without uveitis who underwent cataract surgery at the Eye Clinic, Sahlgrenska University Hospital, Mölndal, between January 2005 and December 2009 were analyzed.ResultsThe study included 58 eyes with and 283 eyes without uveitis. The most common etiologies were idiopathic anterior uveitis and Fuchs’ heterochromic uveitis. Postoperative visual acuity at 4 weeks was ≥0.5 decimal (0.3 logMAR) in 48 eyes with uveitis (87.3%) compared to 180 non-uveitic eyes (86.1%). Four eyes with uveitis (7.1%) and one eye without uveitis (0.5%) developed postoperative intraocular hypertension/glaucoma. Posterior capsule opacification developed in 11 eyes (19.0%) with and 28 eyes (12.4%) without uveitis.ConclusionWith appropriate perioperative anti-inflammatory regimen and surveillance, modern cataract surgery using phacoemulsification and primary intraocular lens implantation can be performed in patients with uveitis without greater risk of complications, yielding similar visual outcome as in patients without uveitis.

Although combined phacoemulsification, primary IOL implantation, and PPV in children with uveitis resulted in favorable visual outcome and stable inflammation in a majority of children, the technique should so far be reserved for uveitic cases with vitreous pathology.

Managing cataract in the setting of uveitis is known to require specific considerations, although there is no consensus on optimal treatments and surgical approaches (Jancevski & Foster, 2010;Sharief et al., 2018). Uveitis is classified based on anatomical localization (i.e. anterior, intermediate and posterior), with posterior uveitis being more frequently associated with coexisting retinal pathology and thus considered a more severe inflammatory disease. Consequently, cataract surgery