Discovery of Centaurea hyalolepis Boiss. (Asteraceae) in the region of Djelfa (Algeria).Mots clés: Asteraceae, Centaurea hyalolepis, découverte, Djelfa.Key words: Asteraceae, Centaurea hyalolepis, discovery, Djelfa.
Chemical investigation of Retama sphaerocarpa collected in Algeria resulted in the isolation of two megastigmane glucosides, compounds 1 and 2, along with a series of isoflavones and phenol derivatives. Compound 1, named retamoside, was new and its structure was determined by extensive application of spectroscopic methods, including HRMS, 1D and 2D NMR and CD. The anti-inflammatory properties of cooccurring main megastigmane, saurobaccioside B (2) and structurally related vomifoliol (3) on LPS-stimulated murine macrophages RAW 274.7 have been evaluated.
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