A healthy patient presented to Klinikum Altmühlfranken Weißenburg Hospital, Germany, with two morning attacks of painful muscle spasm in the left upper and lower limbs, without altered consciousness. Full examinations, radiological imaging, electroencephalography, lumbar puncture, and autoimmune profile were either normal or not consistent with patient's complaint. Subsequent epileptic episodes were observed on admission day and the following days; thus, the patient was diagnosed with focal epilepsy. The patient started to develop a fever and severe cough on day 4, and SARS‐coronavirus‐2 was confirmed through a nasopharyngeal swap. She received anticonvulsants and symptomatic treatments and completely recovered. This report emphasizes the potential nervous system involvement in severe acute respiratory syndrome‐coronavirus‐2 pathogenesis.

Background: SARS-coronavirus-2 causes coronavirus disease-19 (COVID-19). Materials & methods: We here report epidemiology; clinical, radiological and laboratory characteristics; and outcomes of COVID-19 in 19 patients confirmed by reverse-transcriptase–PCR. Results: In 19 PCR-confirmed cases (median age 69 years; 63% males), the most common presentations were fever (79%), cough (79%) and fatigue (79%). The most common comorbidities were hypertension (47%), hypothyroidism (32%) and cardiac diseases (32%). All patients received symptomatic treatment. Ampicillin/sulbactam was prescribed for 50% of cases. Also, 13 (68.4%) recovered and discharged, 9 (47.3%) needed intensive care unit admission and 4 (21.1%) cases died Conclusion: The included cases had variable clinical outcomes following supportive and antibiotic treatments. These findings may contribute to development of more effective strategies for infection control.

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease-19 (CoVID-19). The virus has exhibited unprecedented human to human transmission and progressed into a pandemic over a short duration. Aim To report the epidemiology; clinical, radiological, and laboratory characteristics; and outcome of SARS-CoV-2 infection in 19 patients in Germany. Methods Retrospective analysis of 19 patients contracting SARS-CoV-2 infection confirmed by PCR in Germany between March 1, 2020 and March 31, 2020. Results In 19 PCR-confirmed SARS-Cov-2 virus infection (median age 69 years; 12 (63%) males), the most common presentations were Fever (79%), cough (79%), fatigue (79%), and dyspnea (42%). The most common comorbidities were hypertension (47%), hypothyroidism (32%), and cardiac diseases (32%). According to chest X-ray, 15 (79%) of patients had abnormal chest X-rays; of these, 13 had bilateral chest infiltrates and two had unilateral infiltrates. Lactate dehydrogenase and C-reactive protein (CRP) were elevated in all patients at baseline investigations; 343 U/L (169-931 U/L) and 8 mg/dL (1-17 mg/dL), respectively. Of the 19 cases, 13 (68.4%) recovered and discharged, 9 (47.3%) needed ICU admission, and 4 (21.1%) cases died. Conclusion Among the 19 patients diagnosed with SARS-CoV-2, mild respiratory tract infections symptoms were frequently reported. Some patients required supplemental oxygen and had variable clinical outcomes following supportive and antibiotic treatments. These findings may contribute to the development of more effective strategies of infection control.