Introduction: The different mood states in our daily life can affect our mental and emotional health. The aim of our study was to explore photoplethysmography to record heart rate variability as a marker of changes in mood states in our daily life.Materials and Methods: Two groups of affective pictures categorized into positive and negative sets were shown to thirty subjects on two different consecutive days with simultaneously recording of heart rate variability for 5 minutes by photoplethysmography technique. Immediately after recording on each day, 0-9 self-assessment scale was used to assess the mood state of the subject after viewing the set of pictures.Results: Sympathetic domains of heart rate variability like low frequency (200.3 ±4.1 vs. 166.7 ±2.8, p<0.05), low- and high frequency ratio (1.45 ± 0.21 vs. 0.55 ± 0.07, p<0.05) and low frequency (55.8 ± 2.9 vs. 38.6 ± 2.8, p<0.05) significantly increased in negative mood state condition as compared to positive mood state condition. High frequency (157.9 ± 3.9 vs. 264.3 ± 5.3, p<0.05) and high frequency (44 ± 2.9 vs. 61.2 ±4.2, p< 0.05) significantly increased in positive mood state condition as compared to negative mood state condition. There was significant increase in heart rate (78 ± 2.99 vs. 73 ± 3.11, p<0.05) in negative mood state as compared to positive mood state.Conclusions: Increase in sympathetic activity during negative mood state and increase in parasympathetic activity during positive mood state measured by photoplethysmography technique validates this easy and noninvasive mental assessment tool to determine different mood states.

Background: Vaccination is the most effective method to prevent the spread of infectious diseases and helps reduce mortality rate and economic costs associated with the pandemic. Despite these advantages, misinformation and rumors on vaccine safety and efficacy can lead to increased hesitation or fear towards vaccination. This study reports the incidence of adverse events following Covishield vaccination, their associated factors, medication used for their management, and attitudes about vaccine safety. Methods: A randomised cross-sectional study was conducted from the sample of Covishield-vaccinated individuals from a secondary hospital, two primary health centres, and 36 health posts in eastern Nepal. Individuals (n = 602) were randomly sampled from a population (N = 1013) who had received the first dose of Covishield, namely frontline workers and other high-risk populations. The second-round follow-up had 516 participants. Association of incidence and severity of post-vaccination events with socio-demographic variables, comorbidity status, and medication use were estimated. Results: Among the 79.9% of participants who reported adverse events after receiving the first dose, two-thirds of complaints were mild (67.4%, 95% CI 63.2–71.6) with the most common complaint being pain at the injection site (86.5%). Paracetamol or its combination were used in majority cases (95.2%). After the second dose, only 31.2% (95% CI 27.2–35.2) reported adverse events, the overwhelming majority of which were mild (95.7%) and required a lower frequency of medication (7.4% vs. 25.9%). Adverse Event following immunization were significantly associated with being 18–30 years old (χ2 = 16.9, df = 3, p < 0.001) and female gender (χ2 = 5.2, df = 1, p < 0.05). Prior to the first dose, 86.0% of participants (95% CI 83.3–88.8%) perceived the vaccine to be safe, and 96.0% recommended the vaccine post-vaccination, while 96.8% were interested in receiving the second dose.Conclusions: Overall, vaccination associated events were mild and majority were managed with paracetamol or its combination. Effective counselling about adverse events before vaccination should be prioritised to reduce hesitation and fear.

Introduction: Working memory is a kind of short term memory important for reasoning and guiding decision-making and behavioral process.Objective: The goal of the present research was to study the outcome of single bout of acute moderate-intensity exercise on working memory.Methodology: Twenty two male subjects were asked to perform working memory task by 2n back task in baseline resting, immediately after exercise and after five minute of exercise session. 3 minute step test procedure was used as a moderate intensity exercise intervention.Results: The percentage correctness of 2n back task of working memory was found to be 64.36% for baseline resting condition, 78.01 % for immediately after 3-minute step test and 80.70% for 5 minute after the exercise. In both exercise session (i.e. immediately after exercise and after 5 minute of exercise), significant improvement (p value <0.05) in working memory was seen as compared to the baseline resting session while no such significant beneficial improvement was seen when compared between immediately after exercise and after 5 minute of exercise.Conclusion: Improvement in working memory after moderate exercise intervention was seen, which is important for learning and memory and decision-making.  BJHS 2018;3(2)6:484-487.

Objective: There are conflicting reports in the literature concerning the time and frequency domain parameters of heart rate variability (HRV) in athletes. Furthermore, the exact impact of different sports disciplines on cardiac autonomic function is unclear. Thus, the study was destined to assess and compare HRV in the time and frequency domains between elite Nepalese football players and non-athletes. Methods: Temporal and spectral HRV parameters determined from 5-minute continuous ECG during supine rest were studied in 27 elite male football players (age: 22.74±2.52 years) with excellent cardiorespiratory fitness, and 30 non-athletic male (age: 23.41±2.95 years) volunteers (control group). All HRV parameters were compared between the groups. Results: Resting heart rate, systolic and diastolic blood pressure were significantly lower and all parasympathetic-related time and frequency domain indices, including root mean square of successive differences [RMSSD, [HFnu,)%, p=0.001]), were higher in footballers compared to non-athletics. Similarly, standard deviation of all NN intervals (SDNN), determinant of global HRV, was higher in players (p=0.003). Furthermore, the power spectral components low frequency in normalized unit (LFnu), a sympathetic marker, and LF/HF, which reflect sympatho-vagal balance, were significantly lower in players. Conclusion: The footballers had enhanced parasympathetic (higher RMSSD, HF and HFnu, and lower LF/HF ratio) and diminished sympathetic (lower LFnu) tone on heart. Football playing has favorable effect on the cardiac autonomic profile as indicated by high global HRV (higher SDNN).

Introduction: Anthropometric measurement of dry bones are helpful to estimate the stature. It is useful for differentiating unidentified bodies, skeletal remains, surgical procedures and are helpful for anthropologists, anatomists, forensic and surgery. Objective: The objective of this study was to find the morphometric measurements of dry Humerus bone available at Birat Medical College and Teaching Hospital of Eastern Nepal. Methodology: A cross- sectional study was conducted from 28th June- 28th July 2019 in the department of Anatomy of Birat Medical College and Teaching Hospital by taking 59 dry humerus bone. Various parameters such as maximum length, circumference of surgical neck, epicondylar breadth together with position and number of nutrient foramina were measured. Data was collected using osteometric board, vernier caliper and tape. The number, direction and location of nutrient foramina were observed macroscopically by using a fine wire. Ethical clearance was taken from Institutional Review Committee of Birat Medical College and Teaching Hospital. Results: Among 59 dry humerus bone, majority (32) were left humerus. No statistical significant difference was found in morphometric measurements between right and left side of dry Humerus bone. The single nutrient foramen was present in 85.18% and 81.25% of right and left humeri respectively. Double nutrient foramina in 14.81% of right humeri and 15.62% of left humeri. Triple nutrient foramina was only seen in left humeri (3.12%). Conclusion: Single nutrient foramen is most common in both sides of humeri. No statistical significant difference was found between right and left humeri in the different parameters such as maximum humeral length (MHL), vertical diameter of superior articular surface (VDSAS), circumference of surgical neck (CSN), circumferences of middle shaft (CMS), epicondylar breath (EB), medial epicondyle to capitulum (ME - C), transverse diameter inferior articular surface (TDIAS), maximum transverse diameter of trochlea (MTDT), anteroposterior diameter of the trochlea (APDT) and position of nutrient foramina (PNF).