PubMed is a free search engine for biomedical literature accessed by millions of users from around the world each day. With the rapid growth of biomedical literature—about two articles are added every minute on average—finding and retrieving the most relevant papers for a given query is increasingly challenging. We present Best Match, a new relevance search algorithm for PubMed that leverages the intelligence of our users and cutting-edge machine-learning technology as an alternative to the traditional date sort order. The Best Match algorithm is trained with past user searches with dozens of relevance-ranking signals (factors), the most important being the past usage of an article, publication date, relevance score, and type of article. This new algorithm demonstrates state-of-the-art retrieval performance in benchmarking experiments as well as an improved user experience in real-world testing (over 20% increase in user click-through rate). Since its deployment in June 2017, we have observed a significant increase (60%) in PubMed searches with relevance sort order: it now assists millions of PubMed searches each week. In this work, we hope to increase the awareness and transparency of this new relevance sort option for PubMed users, enabling them to retrieve information more effectively.

DES appear to reduce the restenosis rate and clinical end points, and appear to be more cost effective than BMS. Patient-related factors (eg, sex, hypertension and unstable angina) are important variables that affect the restenosis rate. Noninvasive stress testing had high positive and negative predictive values. Therefore, based on the present study, noninvasive stress testing is suggested before routine angiography at follow-up, which will reduce the need for repeat coronary angiography.

Due to large number of entities in biomedical knowledge bases, only a small fraction of entities have corresponding labelled training data. This necessitates entity linking models which are able to link mentions of unseen entities using learned representations of entities. Previous approaches link each mention independently, ignoring the relationships within and across documents between the entity mentions. These relations can be very useful for linking mentions in biomedical text where linking decisions are often difficult due mentions having a generic or a highly specialized form. In this paper, we introduce a model in which linking decisions can be made not merely by linking to a knowledge base entity but also by grouping multiple mentions together via clustering and jointly making linking predictions. In experiments we improve the state-of-the-art entity linking accuracy on two biomedical entity linking datasets including on the largest publicly available dataset.

Diversified retrieval is a very important problem on many e-commerce sites, e.g. eBay and Amazon. Using IR approaches without optimizing for diversity results in a clutter of redundant items that belong to the same products. Most existing product taxonomies are often too noisy, with overlapping structures and non-uniform granularity, to be used directly in diversified retrieval. To address this problem, we propose a Latent Dirichlet Allocation (LDA) based diversified retrieval approach that selects diverse items based on the hidden user intents. Our approach first discovers the hidden user intents of a query using the LDA model, and then ranks the user intents by making trade-offs between their relevance and information novelty. Finally, it chooses the most representative item for each user intent to display. To evaluate the diversity in the search results on e-commerce sites, we propose a new metric, average satisfaction, measuring user satisfaction with the search results. Through our empirical study on eBay, we show that the LDA model discovers meaningful user intents and the LDA-based approach provides significantly higher user satisfaction than the eBay production ranker and three other diversified retrieval approaches.

A novel Fe-Cu-C based self-lubricating composite is developed, wherein Calcium fluoride (CaF2) has been used as a solid lubricant. CaF2 is added in varying weight percentages of 3, 6, 9 and 12% to the base matrix comprising of Iron, Copper and Graphite (Fe-2Cu-0.8C). The composites were fabricated through Powder Metallurgy using uni-axial compaction and sintering. The developed composites were tested for friction and wear characteristics using a pin-on-disc configuration, conducted at a speed and load of 10 m/s and 20 N respectively. All tests were conducted at high temperature of 500°C for a constant sliding distance of 4000 m. Results show low coefficient of friction for the composites with 3-9 wt% CaF2 making them self-lubricating. Due to testing at high temperature, weight gain was observed in all the composites because of oxidation. The increase in weight gain was observed to be dependent on the CaF2 content. Adhesion, ploughing and delamination were identified to be the prominent wear mechanisms of the developed self-lubricating composites as revealed by SEM analysis.

Publications in the life sciences are characterized by a large technical vocabulary, with many lexical and semantic variations for expressing the same concept. Towards addressing the problem of relevance in biomedical literature search, we introduce a deep learning model for the relevance of a document's text to a keyword style query. Limited by a relatively small amount of training data, the model uses pre-trained word embeddings. With these, the model first computes a variable-length Delta matrix between the query and document, representing a difference between the two texts, which is then passed through a deep convolution stage followed by a deep feed-forward network to compute a relevance score. This results in a fast model suitable for use in an online search engine. The model is robust and outperforms comparable state-of-the-art deep learning approaches.

We describe a Deep Learning approach to modeling the relevance of a document's text to a query, applied to biomedical literature. Instead of mapping each document and query to a common semantic space, we compute a variable-length difference vector between the query and document which is then passed through a deep convolution stage followed by a deep regression network to produce the estimated probability of the document's relevance to the query. Despite the small amount of training data, this approach produces a more robust predictor than computing similarities between semantic vector representations of the query and document, and also results in significant improvements over traditional IR text factors. In the future, we plan to explore its application in improving PubMed search.

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