Aims: The main aim of the study is to prospect the phytochemical constituents in the Clerodendrum serratum
(Linn).Moon by HR-LCMS Analysis and PASS predictionMethods:The leaves of the Clerodedrum serratum (Linn).Moon
was extracted with Ethanol at room temperature for 24 hours.The bioactive compounds of Clerodendrum serratum have
been separated and identified using HR-LCMS.Results: Preliminary phytochemicals analysis revealed the presence of
tannins, quinines, saponins, terpenes, flavonoids, steroids, phenolic compounds and carbohydrates. Total 12
compounds identified were selected for further screening by molecular docking studies.The spectral analysis revealed
different compounds Pindolol,Umbelliferon, 1 alpha, 25-dihydroxy-26, 27-dimethyl-20, 21, 22, 22, 23, 23-hexadehydro24a-homovitamin D3, Hydroxyhydroquinone, Phenylacetic acid, Kynurenine, cholic acid glucuronide, Megastigma -3,
7(E), 9 triene , Alloaromadendrene, Ethambutol ,α santalol and many other compounds were identified as low level.
Conclusion: The result of this study offers a platform of using Clerodendrum serratum (Linn) Moon. As herbal
alternatives for various diseases and it can be used as functional andpharmaceutical agent.