Introduction: Polyps of gastrointestinal tract are not uncommon specimens received in surgical pathology laboratory. With advent of advanced endoscopy it is now possible to precisely sample polyps and determine its nature; weather benign, malignant or with malignant potential. Present study was performed with aim to study incidences of various histological types of polyps of gastrointestinal tract, to study its clinical presentation and to study polyps in relation to their size and site, in a tertiary care hospital. Materials and Methods: A retrospective and prospective analysis of 189 cases of gastrointestinal polyps was carried out over a period of eight and half years. Relevant clinical details of patient, size, number, size and presence of stalk etc. were noted. Specimens were studied for gross and microscopic examination after fixation of specimen with 10% formalin and microscopically examining H & E slides. They were classified according to site and various histological types. Results: Overall, we analysed 189 cases of gastrointestinal polyps. Commonest site was large intestine and commonest type was Juvenile polys, followed by neoplastic polyps, hyperplastic polyps, inflammatory pseudo polyps, hamartomatous polyps, inflammatory fibroid polyps and 2 cases of Familial polyposis coli were note. Conclusion:Present study reveals that gastrointestinal tract had wide spectrum of non-neoplastic as well as neoplastic polyps. They have different clinical significances and therapeutic implications. Histopathology play pivotal role in arriving at final diagnosis which enables to study detail incidences and helps to differentiate non-neoplastic diseases with clinical presentation of malignancy. Incidence of various polyps in based on institutional data and may not reflect incidence of state or nation.

Present study was conducted to analyze the histopathological changes associated with the gallbladder disorders in order to ascertain the incidence, prevalence, distribution as well as the histomorphologic spectrum of gall bladder lesions. Materials and methods A 5 years (from January 2004 to December 2008) retrospective and prospective analysis of 1096 cholecystectomy specimen received in surgical pathology department was done. Cholecystectomies received were opened longitudinally, examined for gross features like

Background:The pattern of diseases causing adult nephrotic syndrome varies globally as well as in India. The aim of our study was to analyze the spectrum of patients with biopsy proven nephrotic syndrome in adults over 15 years, in respect with incidence, age distribution and correlate the clinicopathological features, electron microscopy and immunofluorescence. Methods:We have evaluated and analyzed retrospectively 263 renal biopsies of adult nephrotic syndrome over a consecutive period of 16 years (January 2000 to December 2015) in our tertiary care Hospital.Result: In our study of 235 (89.35%) adequate renal biopsy cases overall male predominance was seen (M: F ratio 1.7:1) with maximum males noted in diabetic nephropathy (M: F ratio 4:1) while SLE was seen exclusively in female (M: F ratio 0:6). Minimal change disease (26.38%), followed by MPGN (16.17%) and FSGS (15.74%) were the common histopathological lesions. In 15-45 years age majority of 78.72% cases were observed with prominently histomorphological pattern as MCD( 25.10%),followed by FSGS ( 13.61%) & MPGN (13.19%). In 45-85 years age , 21.28% cases majority were of membranous glomerulonephritis (5.10%) and diabetic nephropathy (4.25%). Primary glomerular diseases accounted for 78.3% cases commonest was MCD (26.38%) and secondary glomerular diseases in 21.7% of cases, most common being amyloidosis (7.23%) Light microscopy, immunopathology findings correlated with electron microscopy findings in 79 cases (91.86%) out of 86 cases. Sample error was main reason of non correlation of EM & LM diagnosis, especially in FSGS. Conclusion:This data analysis is essential to study the prevalence of biopsy proven renal diseases and its variation and distribution as per age .Which can improve the understanding of utility of renal biopsy for future research of renal parenchymal diseases in adults.