Background: The likelihood of newborns acquiring severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) from infected mothers has raised concerns among families and clinicians worldwide. The disease seems to be mild in children and, to date; there are few reports in neonatal population. The aim of the study was to study the Prevalence of Neonatal SARS-CoV-2 infection in a tertiary care teaching hospital. The objective of the study was to study correlation of clinical features and laboratory parameters among SARS-CoV-2 positive neonates.Methods: Prospective observational study conducted in a dedicated COVID-19 tertiary care hospital and Postgraduate Institute in Pune, Maharashtra between May 2020 and August 2020 on a sample size of 55 COVID suspect neonates as they were admitted and diagnosed during the pandemic.Results: Out of 250 COVID positive mothers admitted, 55 COVID suspect neonates were admitted as their mothers were symptomatic. Among 55 suspect neonates, 11 turned out to be positive (20%). Out of 11 COVID positive neonates, tachypnea with requirement of non-invasive O2 in 2 (18%), feeding intolerance in 2 (18%), fever in 2 (18%) rash 1 (9%) was seen. out of the 11 COVID positive neonates admitted, 45% had elevated D-Dimer levels, 36% had elevated Leucocyte counts, 27% each had raised serum ferritin and fibrinogen levels and 18% had raised CRP Levels.Conclusions: We conclude that inspite of the first wave of COVID seen in neonates which was rare then, clinical and laboratory markers showed a good co-relation in our study in all neonates who were COVID positive but there was no radiological co-relation in any. However, all recovered with symptomatic treatment without any specific COVID treatment.
Background: A questionnaire-based study was conducted in rural schools of Maval taluka of Pune district to assess the knowledge about hand washing practices and behavior in school going children. It is well known that hand contamination plays a major role in faeco-oral transmission of diseases. Hand washing is well recognized preventable tool in disease prevention.Methods: A questionnaire-based study on hand washing practices and behavior in school going children in Maval taluka was carried out on 340 volunteers (students) from grade 6 to 8 of rural area of Maval taluka, Pune District. Maharashtra. Statistical analysis was done by using percentages and proportions.Results: A total of 340 students from grade 6 to 8 participated in the study. Majority were from age 11-13 years (n= 147). Almost all (n=320, 93%) were knowing the practice of handwashing. Majority (n=209,61%) were using soap in some form for cleaning of hands. Many (n=250,73%) were having practice of washing hands before meals. Almost all (n=309, 91%) were knowing the reason for washing of hands. The benefits and prevention of diseases were known to majority of students (n= 295,87%) Nail trimming was done once a week in almost all students.(n=250,73%) Reason for trimming of nails was known to many (n=326, 96% ) as it prevents the spread of the disease, only (n=14,4% ) were not aware of the reason for trimming of the nails. About (n=201, 59 %) of mothers had formal education upto tenth std.Conclusions: Majority of the students used water and soap for hand washing and knew the importance of hand cleaning to prevent many diseases.
Background: Children with moderate acute malnutrition (MAM) have an increased list of mortality, infections and impaired physical and cognitive development compared to well-nourished children. The Objectives of this study were to diagnose Severe Acute Malnutrition (SAM) and Moderate Acute Malnutrition (MAM) using WHO growth charts as a criterion and to compare the WHO classification with the IAP classification in the diagnosis of SAM and MAM.Methods: A two-year duration cross-sectional study conducted in Pediatric outpatient clinic of a rural hospital from January 2013 to December 2014. In case of moderate acute malnutrition (MAM) was diagnosed as weight-for-height >-3 but <-2 Z scores of the median according to WHO growth standards. We defined MAM as mid-upper am circumference (MUAC) of >11.0 cm and <12.5 cm with no bilateral pitting edema and SAM as MUAC less than 11.5 cm. We compared the values with the IAP charts for diagnosis of malnutrition. Our set up is not a nutrition rehabilitation centre, feeding programmes were not implemented.Results: The distribution of prevalence of SAM and MAM differs significantly across three age groups studied (P-value <0.001). However, it did not differ significantly between boys and girls aged between 6 months to 6 years (P-value >0.05). Of 90 SAM cases, 55 cases (61.1%) had Grade 1 IAP grade of malnutrition, 28 cases (31.1%) had Grade 2 IAP grade of malnutrition, 7 cases (7.8%) had Grade 3 IAP grade of malnutrition. None of the SAM cases fell in Grade 4 IAP. The distribution of prevalence of SAM and MAM differs significantly across various IAP grades of malnutrition (P-value <0.001).Conclusions: The IAP charts used for diagnosing malnutrition did not have any comparative value with the WHO charts used for the SAM MAM detection. WHO grading of SAM and MAM is more sensitive than IAP grading in early diagnosis of under nutrition and facilitate early treatment. Not having a targeted nutrition-specific intervention to address MAM in this set up places these children with MAM at excessive risk of adverse outcomes. Further preventive and curative approaches should urgently be considered.
Objectives: 1.To estimate the level of serum 25 hydroxyvitamin D [25(OH)D] levels in patients of Acute respiratory tract infections (ARTI) admitted in the pediatric ward of a rural hospital. 2. To study the association between vitamin D deficiency and respiratory tract infections by estimating serum 25 hydroxyvitamin D [25(OH)D] levels in these patients. Materials and Methods: A hospital-based observational study was carried out in the patients admitted for ARTI from pediatric ward over 6 month's duration. A total of 52 subjects between the age group 2 to 60 months were selected for the study. Results: Average Vitamin D levels were 39.6 ng/dl. On the basis of results of Vitamin D level it has been divided into four categories namely, deficient, insufficient, sufficient, and toxic. The number of children with deficient levels and insufficient levels were 33 (63%), sufficient levels were 11 (21%), where as those with toxic levels were 8 (15%). Conclusion: Vitamin D levels are found to be lower in 63% cases of ARTI. However 15% children had Vitamin D levels in a toxic range. Therefore Vitamin D should not be arbitrarily administered in a therapeutic dose in all children with ARTI. Vitamin D supplementation is to be given after estimation of Vitamin D levels in all ARTI patients. There is a need of more studies to be done on a larger sample size to reach to a certain conclusion.
Moyamoya cerebral angiopathy is characterized by progressive stenosis or occlusion of the internal carotid artery or its branches with subsequent development of basilar collaterals. It is commonly seen in Asian population. Authors present a case report of a 12 year-old boy with Multidrug resistant tuberculosis with Moyamoya disease. Moyamoya disease rarely coexists with tuberculosis. However, we can infer that tuberculosis may coexist in a patient in a patient of Moyamoya disease.
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