A splenic lesion often represents a diagnostic challenge due to relative scarcity and the broad differential diagnosis. Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is usually encountered only incidentally. Although benign, patients with SANT often receive splenectomy, due to its rarity, diagnostic uncertainty and sometimes intimidating imaging morphology and size. Imaging features on computed tomography, magnetic resonance and positron emission tomography have a high diagnostic value for SANT and help differentiate this entity from other splenic lesions. When the imaging parameters are matched with core needle biopsy tissue analysis, further watchful waiting can be recommended in order to avoid splenectomy.
(HPC) in the left gluteal musculature 10 years previously. The patient had also undergone multiple pulmonary metastases resec-tions. An ultrasound of the occipital region revealed a heterogeneous soft tissue mass with destruction of the occipital bone of up to 6 cm (Figure 1). Computed tomography (CT) of the brain showed an extra-axial mass in the fossa posterior extending through the tentorium and lysis of the overlying occipital bone (Figure 2). On MRI the mass was isointense to grey matter on both
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