Dear Editor, Cutaneous and extracutaneous autoimmune diseases (ADs) have rarely been reported in association with COVID-19 vaccine. 1,2 We described herein a case of sudden onset of vitiligo occurring after the first dose of COVID-19 vaccine. To date, only two cases of vitiligo in COVID-19-vaccinated patients have been described. 3 A 33-year-old female presented us with a 45-days history of milky-white well-demarcated, oval and liner-shaped macules on her trunk, neck and back (Figure 1A,B) which had appeared 1 week after receiving her first dose of Pfizer-BioNTech COVID-19 vaccine. The second dose of vaccine was injected 1 months later without the appearance of new macules.
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