Background: The study was aimed to evaluate the effects of combined spinal epidural analgesia on the duration and outcome of labour in nulliparous parturients in comparison with parturients not receiving any analgesia.Methods: It is a prospective clinical study. The present study was carried out in the labour ward, KIMS Hubli. Nulliparous parturients in early active labour were divided into two groups. CSE group (n=40) and non CSE group. In present study CSE was performed with intrathecal 1.25mg of levobupivacaine with 25mcg fentanyl initially and this was followed by epidural boluses of 10ml of 0.0625% Levobupivacaine with 2mcg/ml fentanyl through the epidural catheter whenever the patients’ pain score is more than 4.Results: Mean duration of active labour was 139+/-41.2min in CSE group and 251.1+/-57.9 min in non CSE group. The rate of cervical dilatation was 2.63+/-0.66cm/hr. in CSE group as compared to 1.45+/-0.38cm/hr in non CSE group. The duration of second stage of labour was similar in both groups. The spontaneous vaginal deliveries was77.5% in CSE group as compared to 79.5% in non CSE group. Assisted vaginal deliveries were 15% in combined spinal epidural analgesia group compared to 10.3% in non CSE group which was statistically insignificant. LSCS was 7.5% in control CSE group compared to 10.3% in non CSE group. Maternal satisfaction was excellent in majority of parturients in CSE group. The perinatal outcome was not affected in CSE group. The incidence of complications were very minimal in present study.Conclusions: Authors concluded that combined spinal epidural analgesia provides safe and excellent analgesia with no significant increase in the caesarean section and instrumental delivery rates. In addition, CSE decreases the duration of first stage of labour with no effect on perinatal outcome.
Background: HEV infection, a major public health concern, is known to cause large-scale epidemic and sporadic cases of acute viral hepatitis in developing countries. The infection occurs primarily in young adults and is generally mild and self-limiting; however, the case fatality rate is reportedly higher among pregnant women.Methods: Our study, a retrospective observational study, was conducted in a tertiary care center for over a period of 3 years (January 2017 to January 2020) to find out the fetal and maternal outcome in pregnant women with HEV infection.Results: A total of 38 antenatal cases with anti-HEV IgM-positive were included, and the maternal-fetal outcome was analyzed. The maternal mortality was 52.63 % especially during 3rd trimester and post-partum period, including 5 antenatal death. The most common maternal complication was acute fulminant hepatitis (39.5 %), DIC (36.8 %) and hepatic encephalopathy (31.6%). Prematurity (33.3% of total live births) and Still births (32.3 %) including 4 freshes still births were the commonest fetal complications noted.Conclusions: Our study shows that pregnant woman with acute viral hepatitis due to hepatitis E virus infection had a high mortality rate especially during 3rd trimester and post-partum period with poor obstetric and fetal outcome.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.