Background We aimed to evaluate the association of metabolic syndrome (MetS), its components and lipid profile in mid-pregnancy with preterm delivery and preterm premature rupture of membranes (PPROM). Methods This prospective cohort study was conducted on 203 pregnant women between 24-28 weeks of gestation, undergoing the gestational diabetes screening test with 50 gr glucose challenge test (GCT). Fasting serum total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) levels were measured during the week after GCT assessment. Information on the participants' pre-pregnancy weight, demographic/ reproductive characteristics, and height and blood pressure (BP) measurements were documented at baseline entry into the study. Metabolic syndrome was defined as the coexistence of 3 or more of the following criteria: Body mass index (BMI) before pregnancy≥30 kg/m2, BP≥130/85 mmHg, GCT≥140mg/dl, TG≥150mg/dl, and HDL-C≤50mg/dl. All participants were followed through routine prenatal care, up to delivery. Any deliveries or rupture of membranes of less than or equal to weeks of pregnancy, were considered preterm delivery and PPROM respectively. Statistical analysis was performed by SPSS V.20, and p-value of less than 0.05 was considered significant. Results MetS was detected in 10 (4.9%) of participants. Logistic regression analysis showed HDL-C levels, and hypertension had significant effects on spontaneous preterm delivery occurrence [(OR: 0.952, 95%CI: 0.910_0.995), (OR: 1.629, 95% CI: 1.554_1.709) respectively], but no statistically significant results were found for PPROM. Conclusions Low HDL-C levels and hypertension in mid-pregnancy may increase the occurrence of spontaneous preterm deliveries, indicating that MetS and its components should be monitored more closely in pregnancy. Background: In 1998, the World Health Organization (WHO) defined 'metabolic syndrome' (MetS) as a combination of central abdominal (visceral) obesity, glucose intolerance, insulin resistance, dyslipidemia and hypertension (1). This syndrome is a cluster of physiological abnormalities that accelerate the risk of
BackgroundGestational diabetes mellitus carries serious risks to mother and fetus and causes social, mental, and psychological consequences which can affect mothers’ quality of life. Accordingly, this study aims to develop and assess the psychometric properties of quality of life questionnaire for women with gestational diabetes mellitus.MethodsA methodological study of sequential exploratory mixed method was developed and implemented. It included qualitative (development of a quality of life questionnaire for mothers with GDM) and quantitative (assessment of psychometric prosperities of quality of life questionnaire for mothers with GDM) phases.ResultsBased on the findings of the qualitative phase and literature review, the primary questionnaire was prepared with 142 items. The outcome of face validity and content validity assessment was a 67-item questionnaire. S-CVI and S-CVR turned out to be 0.92 and 0.68, respectively. The results of exploratory factor analysis yielded an instrument with 36 items in five domains including concerns about high-risk pregnancy, perceived constraints, disease complications, medication and treatment, and support. Five factors explained 46.68% of the total variance of the questionnaire. The results indicated a moderate and significant correlation between the questionnaire of “Diabetes Clients Quality Of Life” and the researcher-made questionnaire (r = 0.63). Cronbach’s alpha coefficient for the entire scale was 0.93 and the intra-class correlation coefficient was 0.95.ConclusionQuality of life questionnaire for mothers with GDM is a valid and reliable tool capable of measuring the quality of life of women with GDM.
Objectives: High-risk pregnancies can affect the quality of life (QOL) of pregnant women due to their complications. QOL involves different dimensions including physical, psychological, and social health of the individuals. Assessing the QOL, especially in mothers with gestational diabetes is important in planning for maternal and newborn care and understanding the need for care for policymakers and the health care association. Therefore, the present study aimed to review the effects of gestational diabetes on QOL during pregnancy. Materials and Methods: In this study, articles indexed in several databases such as PubMed, Science Direct, Scopus, Google Scholar, SID, and Magiran were obtained among which, those related to the QOL of mothers with gestational diabetes were extracted and evaluated based on the aim of the study. Results: The series of the reviewed studies included 10 articles on the physical, psychological, and social dimensions of the QOL of mothers with gestational diabetes. Most of the examined articles failed to find any significant change in the physical dimension of QOL of mothers with gestational diabetes. The psychological effects of gestational diabetes were diverse and less understandable, therefore, different studies obtained contradictory results in this regard. Three out of four studies examining the social dimension of QOL of women with gestational diabetes showed that mothers’ QOL could be jeopardized by social dimension. Conclusions: In general, the results revealed that gestational diabetes could affect various physical, psychological, and social dimensions of the QOL of mothers. In addition, adequate education should be provided for mothers with diabetes in order to reduce their fear, anxiety, and depression concerning gestational diabetes.
Background Gestational diabetes mellitus carries serious risks to mother and fetus and causes social,
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