Dentigerous cyts are form of benevolent odontogenic cyts which are related to crowns of permament teeth. Often, they are described as unilocular radiolucent lesions and barely seen in childhood era. This article aims to show a case about 11 year old boy having a dentigerous cyst associated with the mandibular canine and a premolar. Extraction of the primary molars and marsupialization of the lesion is also included in this method of treatment. After 9 months of the treatment, impacted teeth spontaneously erupted. Therefore, if we aim to manage of dentigerous cysts in children conservatively, marsupialization might be considered as first and foremost treatment method.

Fractures in the jaw bones could present themselves differently according to the strength of the force and the bone’s ability to absorb the impact. The location and type of the fracture is important as well as the cause of the fracture (traffic accidents, melee trauma, pathologic changes). Pre-existing pathologic lesions, position of the teeth and the way they are affected by the fracture have a great influence on the prognosis. Whether to extract the teeth in the line of a fracture has always been controversial among dentists. While some researchers advocate that such teeth should be extracted to avoid complications, others believe that retaining these teeth would benefit the patient more. Most clinicians prefer to treat their patients depending on their own previous experiences. This article aims to establish a guideline on assessing whether to retain or extract the teeth in the fracture line.

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Histopathologic evaluation has been carried out regarding the effect of platelet-rich fibrin and collagen membranes applied on bone recovery. Our objective is to contribute to barrier membrane studies that continue to guide and accelerate bone recovery.

There is strong evidence that nonsteroidal antiinflammatory drugs (NSAID) may exert a significant antiproliferative effect. This study evaluated the influence of NSAID on specific parameters of fibroblastic cells, in vitro, over two-guided bone regeneration (GBR) barrier materials. Fibroblast cells were cultured on bioabsorbable membrane made of collagen (Bio-Gide(R)- BG) and the most common nonresorbable membrane which is made of expanded polytetrafluoroethylene (ePTFE, Gore-Tex(R)- GT). Naproxen sodium (10 mM) was used as an analgesic drug. The fibroblast cells were cultured in vitro for 24 h and examined by scanning electron microscopy (SEM). Cells were cultured in the presence of (3)H-thymidine to study cell proliferation. And also cell numbers and viabilities were measured. The difference between the means for each group were analyzed for statistical significance by Kruskal-Wallis one-way ANOVA followed by post hoc comparisons using the Dunn statistical method. Of all the six groups, the control group stimulated DNA synthesis more than the others. With respect to cell numbers, there was statistically significant difference between the control group and naproxen planted BG membrane group. The interpretation of our SEM images is that these two barriers and naproxen seem to have had the least effect on cellular morphology. These data suggest naproxen have an inhibitory effect on stimulation of DNA synthesis, cell numbers and viabilities. And also lacking adherence of cells to the membranes may be due to the physical properties of the materials.

Toxic doses of cholecalciferol (vitamin D3) were injected subcutaneously (25 into rats for 5 weeks, causing a significant increase of serum alkaline phosphatase (ALP) levels (p < 0.01). Gingival tissue alkaline phosphatase levels were also elevated (p < 0.01). On the other hand, a significant difference was detected between serum calcium levels in experimental and control groups (p < 0.02).

Zinc is a trace element important to bone mineralization as well as, in general, nutrition. It is known that cholecalciferol (vitamin D3) affects bone metabolism. In this study, toxic doses of vitamin D3 were injected subcutaneously (25 micrograms/d) to rats for 5 wk. It caused a significant increase in serum zinc levels (p < 0.02). On the other hand, no significant increase was detected in the other groups. Excessive amounts of vitamin D3 caused bone breakdown and increased the levels of zinc in blood.