A young man presented to our unit with a colloid cyst of the third ventricle. Following successful surgical treatment his parents expressed concern over the possibility of his identical twin brother having a similar cyst. After finding one other case of colloid cysts in identical twins in the world literature we arranged a magnetic resonance scan of the asymptomatic twin. We were sceptical, but much to our surprise the scan also showed a colloid cyst in the third ventricle. Familial colloid cysts of the third ventricle have been reported only rarely. This is the second account of third ventricular colloid cysts in identical twins reported in the world literature. We present case reports of the twins, discuss the world literature on familial colloid cysts and also the genetic implications.
Background: Prolapsed lining of the nasal sinuses are defined as nasal polyp. Diseases of the nasal cavity include viral, bacterial and fungal infections, nasal cavity tumors (benign and malignant) as well as inflammations of the nasal mucosa. This study was undertaken to note the various histopathological patterns of nasal masses, their classification and relative distribution of various lesions with regard to age and sex in our setting.Methods: The study is done for a period of 1 year (July 2018 to June 2019). In this study, 30 patients are selected who presented in our hospital with nasal masses and having multiple types of clinical presentations.Results: Total 30 cases presented as nasal mass. Overall male to female ratio was 2.3:1. Nonneoplastic nasal masses formed the largest group of lesions; 24 cases (80%), followed by 6 cases (20%) of neoplastic nasal masses. Inflammatory polyp was the commonest non neoplastic lesion constituting 22 cases followed by rhinosporidiosis with 2 cases. Out of the 6 neoplastic nasal masses, 5 were benign and 1 was malignant. Out of the benign neoplastic masses, inverted papilloma constituted 3 cases and nasopharyngeal angiofibroma constituted 2 cases. Malignant neoplastic mass was embryonal rhabdomyosarcoma.Conclusions: Nasal obstruction and rhinorrhea are the most common symptoms of presentation. Simple inflammatory nasal polyps are the most common histological pattern seen in our environment, and surgery is the best modality of treatment.
Background: Pigmented lesions are one of the most common cause for dermatological consultation. Most of them are benign, while a majority of them have malignant transformation and are called as melanoma. A careful histopathological interpretation by the pathologist is needed in the diagnosis and management of these lesions. Aims and objectives of the study were- 1. To study the spectrum of various pigmented skin lesions. 2. To establish the correlation between the microscopic pathological findings of various skin lesions with the presenting clinical features.Methods: A 3-year study was conducted in the pathology department of tertiary care centre on all skin biopsy tissue which came as pigmented lesion. The entire skin biopsy is submitted for routine processing and embedded in paraffin wax. 3-5 mm thick paraffin sections of the skin biopsy are stained with H and E.Results: Out of 432 skin biopsies studied during this period, 58 cases were diagnosed as pigmented skin lesions. Of these, the biopsy tissue was inadequate in 5 cases while five cases presented with non-specific findings. Of the remaining cases, 15 were malignant and 33 were benign lesions. Only 18 of these were of melanocytic origin with 8 cases of malignant melanoma and 10 nevi. In the present study an analysis of the clinical diagnosis with the histopathological diagnosis revealed a positive correlation in 54% cases.Conclusions: A good clinical correlation and biopsy with histopathological diagnosis is necessary for the accurate diagnosis and definite treatment of patients with pigmented skin lesions.
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