The plant species belonging to Cucurbitaceae family have a worldwide distribution, but most species can be found in tropical and subtropical countries. A number of the plants belonging to this family have reported important and biological pharmacological activities. Cucurbitaceae member plants are also in use in the folk medicinal system of India. The members of the Cucurbitaceae are annual or perennial herbaceous plants having climbing habit with characteristic tendrils. Plants of this family have many medicinal and nutritional benefits. Therefore, it is important to find out the Ethnobotanical uses in rural region of Ralegaon area and containing active agents possessing pharmacological activity in plants. In this study, we have documented some of the important plants viz., Citrullus lanatus, Lagenaria siceraria, Bryonia lacinosa, Cucumis sativa, Coccinia grandis, Cucurbita pepo, Momordica dioica, Momordica charantia, Cucumis callosus, and Luffa acutangular located in Ralegaon region.
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