OBJECTIVE:The anti-PM/Scl autoantibody has been described in patients with scleromyositis. However, there are scant studies evaluating its prevalence and reactivity in dermatomyositis and polymyositis. METHOD: A cross-sectional, single center study evaluating the anti-PM/Scl autoantibody in 85 dermatomyositis and 32 polymyositis patients, without overlapping syndrome, was conducted between 2000 and 2016. Clinical data and complementary examinations were reviewed from electronic medical records with pre-parameterized information. RESULTS:The mean age of dermatomyositis and polymyositis patients was 41.1 and 42.8 years, respectively. The presence of anti-PM/Scl was observed in 5 (5.9%) dermatomyositis and 2 (6.3%) polymyositis patients. Two of these patients also had the anti-Ku antibody. The relevant clinical manifestations of these 7 patients were constitutional symptoms (100% of cases), muscular (100%), pulmonary (85.7%) and joint (71.4%) involvement, "mechanic hands" (85.7%), Raynaud phenomenon (85.7%) and plantar hyperkeratosis (85.7%). The 7 patients had relapses of disease activity, but at conclusion of the present study, 5 had complete clinical response and 2 complete remission of the disease. CONCLUSION: There is a low frequency of the anti-PM/Scl autoantibody in dermatomyositis and polymyositis patients. In addition, patients with this autoantibody exhibit a similar pattern of manifestations to that of antisynthetase syndrome.
RESUMO:Neste artigo, mostramos como o instituto jurídico da delação premiada funciona como uma forma de obtenção da verdade. Para tanto, em um primeiro momento, recorremos a Foucault para apresentar, brevemente, o funcionamento de diferentes formas de obtenção da verdade jurídica na história. Em seguida, mostramos de que forma a delação premiada é discursivizada nas diferentes leis que tratam do referido instituto ou que o retomam, relacionando-o com outras leis e fazendo-o funcionar como uma forma de obtenção da verdade, vinculada, principalmente, ao inquérito. Na análise das referidas leis, identificamos os deslizamentos de sentido que ocorrem tanto no que diz respeito à figura do delator, quanto em relação a constituição histórica do referido instituto. PALAVRAS-CHAVE: Delação. Discursivização. Verdade. Memória. Delator. ABSTRACT:In this article, we show how the legal institute of plea deal works as a way to obtain the truth. In order to do so, at first, we turn to Foucault to present, briefly, operationally how different ways of obtaining legal truth in history works. Next, we show how the plea deal is discursive in the different laws that refers to this institute or that take it back, relating it to other laws and making it work as a way of obtaining the truth, linked, mainly, to the investigation. During the analysis of these laws, we identify the deviations of meaning that occurs either in which is related to the state"s witness, as well as in relation to the historical constitution of referred institute. KEYWORDS: Plea Deal. Discursive. Truth. Memory. State"s Witness. IntroduçãoNeste artigo, analisamos o instituo negocial penal da delação premiada e a relação desse instituto com a memória acerca das formas de obtenção da verdade. Nesse sentido, a pergunta/problema que direcionou a construção deste texto foi: qual memória o instituto negocial penal da delação premiada retoma? Com base nessa pergunta-
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