This study measured the effect of spiritual care on mental health in mothers of children with cancer. The present quasi-experimental study was with one group pretest posttest design. The findings show that implementation of spiritual care in mothers of children with cancer can improve their mental health.

Screening for breast and ovarian cancers are required due to the late stage at diagnosis and poor survival. Serum CA125 and CA15-3 are important cancerdetecting agents in patients with ovarian and breast cancers, respectively. Elevation of CA125 and CA15-3 level correlates with malignant and non-malignant conditions. Moreover, a series of individual characteristics affect the serum level of these markers. The objective of the present study was to evaluate CA125 and CA15-3 levels in cancer-free postmenopausal women to investigate the impacts of patient parameters on the serum level of these markers. 203 subjects were studied prospectively. Serum CA125 and CA15-3 assessment was done subsequent to the direct interview. The associations between marker levels and presenting features were examined. CA125 and CA15-3 levels were elevated in 35 (17.2%) and 12 (5.9%) of persons, respectively. A higher CA125 level was associated with advanced age (p = 0.046), while a lower level was correlated with hormone replacement therapy (HRT) and having smoking habits (p = 0.000 and p = 0.01, respectively). CA15-3 level was remarkably lower amongst oral contraceptive (OCP) users (p = 0.03). Serum marker levels were not significantly related to menarche age, age at menopause, height, weight, BMI and parity. Serum CA125 is imperative indicator for malignancies of the ovary; however, personal and medical factors influence its serum level. A fair interpretation of results must be due to an accurate attention to the individual characteristics.

Background: Multiple sclerosis (MS) burden of disease has been described by reporting the disability-adjusted life years (DALY) index. So far, no study has assessed the trend of MS DALY rates over time. Method: Age-standardized MS DALY rates for both sexes were reported every 5 years from 1990 to 2015 in 195 countries in the Global Burden of Disease Database (GBD) database. To assess the MS DALY rates’ trends in each super region and throughout the world, we applied the Latent Growth Models. We also utilized the linear mixed model to evaluate the effect of development factor on MS DALY rates. Results: Our results showed that 5 out of 7 GBD super regions had negative trends in MS DALY rates during these years and the remaining 2 – Latin America and the Caribbean (slope = 0.196, p < 0.05) and South Asia – slope = 0.057, p > 0.05 – had upward trends. Using a linear mixed model, we found that the mean difference of MS DALY rates was about 25 DALYs higher in developed countries compared to developing ones (p < 0.0001). Conclusion: In general, our findings revealed a global downward trend in the MS DALY rate. We also conclude that MS DALY rates are decreasing both in developed and developing countries, with a steeper slope in the developed world.

Background: Malnutrition is generally due to a lack of nutritional information rather than food deficiency. Therefore, the current knowledge, attitudes, and practice (KAP) of the target audience should be evaluated to eliminate malnutrition. However, KAP varies across demographic status and socioeconomic status (SES). Aim: The associations of nutritional KAP with demographic and socioeconomic variables were evaluated among households living in urban and rural areas of southwestern Iran. Methods: A cross-sectional, population-based study was conducted on 842 household heads (492 urban and 350 rural) using a standardized NUTRIKAP Household Questionnaire. The data evaluating nutritional KAP as well as demographic and socioeconomic information were obtained using a multi-stage cluster sampling method. SES score was also computed. Results: Urban households had a higher level of nutritional knowledge ( p < 0.05) but a lower level of nutritional attitude ( p < 0.001) and practice ( p < 0.001) compared with the rural ones. Rural households with the poorest quintiles of SES were 0.4 times less likely to have good nutritional knowledge (adjusted odds ratio = 0.4, confidence interval: 0.2, 0.9; p < 0.05), compared with higher quintiles. Households with an over-60-years-old household head had significantly higher nutritional attitude ( p < 0.05) and practice ( p <0.01) scores than households with younger ones. Households with male household heads had a higher nutritional practice score compared with households with female ones. Conclusions: These results can indicate the role of demographic and socioeconomic determinants in KAP of Iranian households towards the principle of nutrition and can be effective in prioritizing the implementation of nutritional interventions including nutrition education for them.

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