Geographical information systems (GIS) are increasingly used in England and Wales as a tool to monitor crime and aid community-safety planning. This is despite the widely known limitations of police-recorded data on crime victimisation, and concerns about the quality and specificity of available data on fear of crime. Meanwhile, improving streetlighting is a popular strategy both for improving community safety and for reducing fear of crime. In this paper we report on research carried out in Northumberland, northeast England, which aimed to identify locations most in need of new streetlighting. First, GIS crime hotspot maps and lighting coverage maps were analysed to identify potential areas to target. Qualitative rapid appraisal techniques were then used in these areas to explore local residents' perceptions and understandings of the relationships between streetlighting, victimisation, and fear of crime. The qualitative data were used to interpret the hotspot maps further, and to inform the location and type of streetlighting interventions. The research demonstrates that people's experiences of crime and fear, and their understandings of the relationships these have to streetlighting, are complex and reflective. At most, streetlighting was held to have a marginal and even then contradictory influence on the problems of crime and fear that people face. The implications are considered. We conclude that qualifying the outputs of GIS mapping was essential in this case, and has wide potential in critical policy research to promote more inclusive knowledge and more effective decisionmaking.

Mobile phone ownership has spread rapidly among young people in the UK. This article contributes to an expanding body of literature which is examining the consequences of this phenomenon for urban life. Our focus is the impact of mobile phones on young people's geographies, particularly their own and their parents’ fears about their safety in public spaces. Quantitative and qualitative findings are presented from two research projects in Gateshead, north‐east England on crime victimization and leisure injury risk for young people, in which the role of mobile phones in managing and negotiating safety emerged as significant. The article highlights the different ways in which young people and parents are using mobile phones for this purpose, and asks whether they are best viewed as technologies of surveillance or empowerment. We also raise questions about the efficacy of mobile phones in protecting young people from risk and fear, in particular examining the mobile as a new site of victimization. Throughout, we emphasize the social unevenness of the uses and impacts of new technologies, which is often underplayed in research. We conclude with the suggestion that although they offer some empowerment to young people in their use of public spaces and their negotiation of risk, mobile phones appear to be reshaping rather than reducing moral panics about young people's presence there. Au Royaume‐Uni, le téléphone mobile s’est répandu rapidement parmi les jeunes. Cet article s’ajoute aux documents en nombre croissant qui étudient les conséquences de ce phénomène sur la vie urbaine. Il s’attache à l’impact des mobiles sur la géographie des jeunes, notamment sur leurs craintes personnelles et celles de leurs parents quant à leur sécurité dans les espaces publics. Il présente des résultats quantitatifs et qualitatifs provenant de deux projets de recherches à Gateshead (nord‐est de l’Angleterre) sur le risque pour les jeunes d’être victimes d’un acte criminel et de se blesser durant un loisir, cas où les mobiles semblent jouer un rôle important pour gérer et négocier la sécurité. L’article met en lumière les différents modes d’utilisation des mobiles à cette fin, par les jeunes et les parents, en se demandant si ces téléphones sont d’abord considérés comme des technologies de surveillance ou de responsabilisation. Il interroge également l’efficacité des mobiles pour protéger les jeunes contre risques et craintes, notamment en envisageant ces téléphones comme nouveau terrain de victimisation. Dans son ensemble, ce travail souligne l’irrégularité sociale des usages et impacts des nouvelles technologies, souvent minimisée dans la recherche. La conclusion suggère que, même s’ils offrent une certaine responsabilisation aux jeunes dans leur utilisation des espaces publics et leur négociation du risque, les téléphones mobiles semblent remodeler, non réduire, les paniques morales liées à leur présence dans ces lieux.

No abstract

Tisotumab vedotin-tftv, an antibody-drug conjugate indicated for the treatment of adult patients with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy, demonstrated clinically meaningful and durable responses with a manageable safety profile in the pivotal phase II innovaTV 204 clinical trial. Based on the proposed mechanism of action of tisotumab vedotin, experience from clinical trials, and the US prescribing information, certain adverse events (AEs) including ocular AEs, peripheral neuropathy, and bleeding have been identified as AEs of interest. This article highlights practical considerations and provides recommendations to support the management of selected AEs associated with tisotumab vedotin. Central to monitoring of patients on tisotumab vedotin is a comprehensive care team comprised of oncologists, advanced practice providers (including nurse practitioners, physician assistants, and pharmacists), and other specialists such as ophthalmologists. As ocular AEs may be less familiar to gynecologic oncology practitioners, adherence to the “Premedication and Required Eye Care” section outlined in the US prescribing information, as well as the incorporation of ophthalmologists into the oncology care team, can help provide timely and appropriate eye care for patients receiving tisotumab vedotin.

No abstract