Introduction:Gastroesophageal reflux disease (GERD) is one of the most common chronic gastrointestinal disorders in adults, it develops when the stomach contents reflux and rise up into the esophagus as a result from lower esophageal sphincter dysfunction. Stomach acid that touches the lining of the esophagus causes symptoms and complications. The classical symptoms of GERD include heartburn, usually after eating, chest pain, and regurgitation.Aim:To measure the prevalence of gastroesophageal reflux disease and determine its risk factors among the students of Shaqra University.Methods:A cross-sectional study was conducted using a structured questionnaire distributed among Shaqra University students after multistage stratification and random sampling technique to stratify students according to gender and the three main colleges in Shaqra city, Saudi Arabia. The sample size was determined to be 435 with the precision of ± 5% and a 95% confidence interval (CI). The questionnaire included demographic data like age, gender, height and weight, lifestyle, and dietary habits. Statistical data were analyzed using the Statistical Package for Social Sciences (SPSS) version 16. Results with a P value of <0.05 were considered statistically significant.Results:A total of 400 [227 (56%) male and 173 (43%) female] participants were evaluated. And 95 participants got a gastroesophageal reflux disease questionnaire score of ≥8 thus determining the prevalence of GERD to be 23.8%. Univariate analysis revealed that gender, smoking, familial history of GERD, high body mass index (>25 kg/m2), fast food, tea, carbonated beverages consumption, quick eating, and sleeping within 1 hour of dinner are associated with symptomatic GERD (P < 0.05).Conclusion:The results show a high prevalence of GERD in Shaqra university students and the presence of many modifiable risk factors which merits the conduction of public health campaigns to raise awareness about the disease and its risk factors.

A 20-year-old male presented with hepatomegaly, jaundice, and itching. Investigation revealed elevated liver enzyme levels, suggesting direct hyperbilirubinemia. Magnetic resonance imaging revealed a stable orientation of the right hemithorax, a relatively small and rotated right hepatic lobe, and a left-rotated intra-abdominal hepatic lobe, with progressive enhancement related to the foci of the hepatic fibrosis. There was an intrahepatic biliary dilatation, reaching 0.8 cm, that was due to biliary compression. There was no evidence of biliary irregularity to suggest a classic primary sclerosing cholangitis pattern. Percutaneous transhepatic biliary drainage and a cholangiogram confirmed the dilation of the left and right bile ducts with smooth, normal drainage via the common bile duct. The symptom management strategy took the form of surgical liver transplantation. The patient demonstrated improvement following transplantation, and his total bilirubin level returned to normal within months. The patient was then discharged in a stable status, and successive follow-up appointments were scheduled every three months to monitor for disease progression or complications.

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