Wheat is the most extensively cultivated crop and occupies a central place in human nutrition providing 20% of the daily food calories. This study was conducted to find both T and ψ effects on wheat germination and the cardinal Ts value; a lab experiment was accomplished using HTT models. Cultivars were germinated under different accelerated aging periods (AAP, 0, 24, 48, and 72 h) at each of the following constant Ts of 15, 20, 25, 30, and 35 °C at each of the ψs of 0, −0.05, −0.1, −0.15, and −0.2 MPa. GR, GP, and other germination parameters (GI, GRI, CVG, SVI-I, SVI-II, GE, and MGT) were significantly determined by solute potential, temperature, and reciprocal action in both cultivars (p ≤ 0.01). Depending on the confidence interval of the model co-efficiently between cultivars, there was no significant difference. Hence, the average of cardinal Ts was 15, 20, and 35 °C for the Tb, To, and Tc, respectively, in the control condition (0 MPa). Hydro-time values declined when Ts was raised to To in cultivars, then remained constant at Ts ≥ To (2.4 MPah−1 in Pirsabak 15 and 0.96 MPah−1 in Shahkar). The slope of the relationship between ψb(50) and TTsupra with temperature when Ts is raised above To and reaches 0 at Tc. In conclusion, the assessed parameter values in this study can easily be used in simulation models of wheat germination to quantitatively characterize the physiological status of wheat seed populations at different Ts and ψs.

Food safety is a priority issue for sustainable global development that can be affected by heavy metals, contributing to morbidity and even mortality in crop growth. Heavy metals often accumulate in the soil due to the use of extensive chemical fertilizers and pesticides; therefore, the current experiment was aimed to determine the effect of glutamate zerovalent iron nanoparticles (Glu-ZVFeNPs) and indole acetic acid (IAA) on physiological mechanism of lead (Pb +2) stress tolerance at 4 and 8 ppm in Zea mays variety. Seeds of the selected variety were collected from Cereal Crop Research Institute Persabaq Nowshera and planted in earthen pots in triplicate in the greenhouse of the Botany Department of the University of Peshawar. Nanoparticles were analyzed via scanning electron microscopy and energy dispersive X-ray analysis. Maximum growth responses were recorded from T12 (untreated + NPs + IAA), while minimum were recorded from T5 (8 ppm) indicating from the minimum amplitude of chlorophyll "a" and "b" contents, root length, shoot length, and root/shoot ratio. T5 (8 ppm) enhanced the values of osmolytes and antioxidant enzymes peroxidase and superoxide dismutase which has been ameliorated by the combined application of Glu-ZVFeNPs + IAA, indicating that the plant may resist the toxic effects of heavy metal stress at high concentration. From the present study, we concluded that adverse result of Pb +2 has been condensed by application of Glu-ZVFeNPs + IAA treatment as compared to the foliar application of IAA and Glu-ZVFeNPs individually.

Background: Soil salinity negatively impacts agricultural productivity. Consequently, strategies should be developed to inculcate a salinity tolerance in crops for sustainable food production. Growth regulators play a vital role in regulating salinity stress tolerance. Methods: Thus, we examined the effect of exogenous salicylic acid (SA) and alpha-tocopherol (TP) (100 mg/L) on the morphophysio-biochemical responses of two wheat cultivars (Pirsabak-15 and Shankar) to salinity stress (0 and 40 mM). Results: Both Pirsabak-15 and Shankar cultivars were negatively affected by salinity stress. For instance, salinity reduced growth attributes (i.e., leaf fresh and dry weight, leaf moisture content, leaf area ratio, shoot and root dry weight, shoot and root length, as well as root−shoot ratio), pigments (chlorophyll a, chlorophyll a, and carotenoids) but increased hydrogen peroxide (H 2 O 2 ), malondialdehyde (MDA), and endogenous TP in both cultivars. Among the antioxidant enzymes, salinity enhanced the activity of peroxidase (POD) and polyphenol oxidase (PPO) in Pirsabak-15; glutathione reductase (GR) and PPO in Shankar, while ascorbate peroxidase (APOX) was present in both cultivars. SA and TP could improve the salinity tolerance by improving growth and photosynthetic pigments and reducing MDA and H 2 O 2 . In general, the exogenous application did not have a positive effect on antioxidant enzymes; however, it increased PPO in Pirsabak-15 and SOD in the Shankar cultivar. Conclusions: Consequently, we suggest that SA and TP could have enhanced the salinity tolerance of our selected wheat cultivars by modulating their physiological mechanisms in a manner that resulted in improved growth. Future molecular studies can contribute to a better understanding of the mechanisms by which SA and TP regulate the selected wheat cultivars underlying salinity tolerance mechanisms.

Objective: Objectives of this study were to compare expression of Programmed Death-Ligand 1(PD-L1) protein in oral squamous cell carcinoma (OSCC) and oral potentially malignant disorder (OPMD) cases; and to compare the PD-L1 protein expression in histological grades of OSCC and also in OPMD's with Dysplasia and without Dysplasia. Materials & Methods: In this study, 25 cases of Oral squamous cell carcinoms, 25 cases of Oral Potentially Malignant Disorders and 10 cases of non-neoplastic oral mucosa (control) cases were included. FFPE blocks of OSCC and OPMD cases were contributed by

Background: The field of measuring Islamic work ethics is a nascent one, and not much work has been cited on the topic. The most cited work is of Mr. Ali from Indiana University, but protestant work ethics and Arabic culture heavily influence that work, so the need was felt for a purpose-built questionnaire for health professionals free from foreign influences. Methods: A mixed-methods exploratory study was performed to develop a novel instrument, following A.M.E.E. guide no. 87, its validity & reliability was established via the measurement of statistical tests such as Cronbach α, Item-Total Correlation & Pearson’s Correlation. Results: Cronbach α was calculated to be 0.9, which is an excellent result. Furthermore, a strong correlation of Islamic ethical constructs Unisation/Tawheed with Itqan/Ihsan; Amanah/Adl and correlation of Itqan/Ihsan with Amanah/Adl; Consultation/Shura; and Unisation/Tawheed was observed. Conclusion: A newly developed data collection instrument was validated following the results of the pilot study. The instrument developed is reliable and fit for purpose. Keywords: Islamic work ethics; measurement tool; medical education; ethics; health professionals.