The study investigates the effects of pomegranate peel extracts on some virulence factors such as the production of some enzymes produced by Proteus spp isolated from different clinical samples. Among 310 different clinical samples, 48 isolates of proteus were obtained, 14 isolates(29.16%)were obtained from urine, 15 isolates (31.25%) were obtained from stool, 7 isolates (14.58%) from ear swabs, 4 isolates (8.33%) were obtained from wounds, 5 isolates (10.41% (from burns and 3 isolates) 6.25%) of the high cervical. The study showed that from 48 isolates of Proteus spp 25 isolates (52.08%) identified as P.mirabilis, 15 isolates (31.25%)of P. penerri, while 8 isolates of P. vulgaris were obtained with a percentage of (16.66%) and it was found that 18 isolates (72%) of P.mirabilis isolates were positive for the production of beta-lactamase enzyme, 24 isolates (96%) are positive for proteases and 14 isolates (56%) produced lipase, while 13 isolates from P. penerri (86.66%) produced beta-lactamases and proteases and 10 isolates (66.66%) produced lipase, also found that 5 isolates (62.5%) of P. vulgaris produced Beta-lactamase and all the isolates (100%) produced protease while 7 isolates (87.5%) produced lipase. It was found that the hot aqueous extract of pomegranate peels inhibited the production of beta-lactamase enzyme in 4 out of 7 isolates that produced this enzyme, while all tested isolates did not produce lipase by using extracts of pomegranate peel extracts. The isolates lost their ability to produce protease enzyme, except for two isolates that were not affected by extracts of pomegranate peel fruits.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.