The prediction of preeclampsia by the urinary calcium/creatinine ratio during the early third trimester was assessed in 190 primigravidas, aged less than 35 years and between 28 and 32 weeks' gestation without pregnancy complications. Preeclampsia developed in 6.8% of the patients. The mean maternal age, gestational age at entry into the study and at delivery, and the average mean arterial blood pressure at entry into the study did not differ significantly between the 13 patients with subsequent preeclampsia and the 177 normotensive patients. The patients with preeclampsia did not have significantly less excretion of calcium than the normotensives.
Laparoscopic ovarian cystectomy is recommended for surgical procedure of endometrioma. The negative impact on ovarian reserve following removal had been documented. Little evidence had been reported for nonovarian originated effects. Objective. To evaluate the impact of laparoscopic ovarian cystectomy for endometrioma on ovarian reserve, measured by serum antimullerian hormone (AMH), compared to nonovarian pelvic surgery. Materials and Methods. A prospective study was conducted. Women who underwent laparoscopic ovarian cystectomy (LOC) and laparoscopic nonovarian pelvic surgery (NOS) were recruited and followed up through 6 months. Clinical baseline data and AMH were evaluated. Results. 39 and 38 participants were enrolled in LOC and NOS groups, respectively. Baseline characteristics (age, weight, BMI, and height) and preoperative AMH level between 2 groups were not statistically different. After surgery, AMH of both groups decreased since the first week, at 1 month and at 3 months. However, as compared to the LOC group at 6 months after operation, the mean AMH of the NOS group had regained its value with a highly significant difference. Conclusion. This study demonstrated the negative impact of nonovarian or indirect effects of laparoscopic surgery to ovarian reserve. The possible mechanisms are necessary for more investigations.
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