Objective: to assess the impact of androgenetic alopecia (AGA)/female patterned hair loss (FPHL) on the quality of life of Pakistani patients using Skindex-29 scale. Study Design: Cross-sectional study. Place and Duration of Study: Outpatient Department of Dermatology, Combined Military Hospital, Lahore Pakistan, from Oct 2020 to Mar 2021. Methodology: Three hundred patients (150 males and 150 females) having androgenetic alopecia (AGA)/female patterned hair loss (FPHL) were selected by consecutive sampling. Skindex-19 questionnaire was used to assess the impact of alopecia on their quality of life. Results: Mean age of study participants was 41.6 ± 12.4 years (range: 18-72 years). Maximum patients (40.7%) had grade-1 severity of alopecia. Most of the patients (37.3%) had disease duration of 1-5 years. Mean global score, symptoms scale score, emotion scale score and function scale score were 31.3 ± 14.8, 22 ± 22.56, 41.67 ± 28.1 and 30 ± 26.5 respectively. Gender and disease duration were statistically significant (p=0.001 and p=0.013 respectively). Conclusion: Skindex-29 can be successfully used in our setup for quality of life studies in AGA/FPHL patients. Females were more severely affected than males as per global scores on Skindex-29.
Objective: To assess patient and observer reported scar quality after Basal cell carcinoma surgery of face using the Patient and Observer Scar Assessment Scale (POSAS). Study Design: Quasi experimental study. Place and Duration of Study: Dermatology Department, Tertiary Care Hospitals at Multan and Karachi and Plastic Surgery Department, Tertiary Care Hospital Multan, from Apr to Sep 2020. Methodology: Patients with basal cell carcinoma that full filled inclusion and exclusion criteria were enrolled by consecutive sampling technique at Dermatology and Plastic Surgery Department after informed consent. Surgical excision was followed by reconstruction of defect either by direct closure or by rotation or advancement flap. Surgical scar was assessed independently at 8 weeks by POSAS. Data was analyzed with SPSS-23. Results: A total of 27 patients were enrolled in study. There were 11 (37.9%) males and 16 (59.25%) females between ages of 45-70 years. Basal cell carcinoma was located on cheek in 15 (55.5%), nose in 9 (33.3%), temple 2 (7.4%) and forehead 1 (3.7%) cases. Direct closure was performed in 6 (22.2%), rotation flaps in 10 (40.7%), and advancement flaps in 11 (40.7%) cases. Mean score of observer opinion about surgical scar between different surgical techniques was not statistically significant (p=0.191). How-ever, mean score of patient opinion of scar between different surgical techniques was statistically significant (p=0.032). Conclusion: POSAS is a valid tool for scar evaluation by patient and observer-reported scar qualities after Basal cell carcinoma surgery.
Objective: To determine mean platelet volume in patients of psoriasis Study Design: Cross sectional study Place and duration of study: Dermatology Department, Pak Emirates Military Hospital Rawalpindi from August 2017 to January 2018. Methodology: Approval from the hospital ethical review committee was taken and a total of 100 patients were enrolled by non-probability consecutive sampling. After an informed written consent, name, gender, age, hospital record number, and phone number of each individual were noted. At the time of enrollment, all the individuals were subjected to complete blood count, bleeding time, fasting blood sugar, fasting lipid profile, renal and liver function tests. Patients with abnormal parameters were excluded from the study. A two ml venous blood sample was drawn from each patient and sent in CP bottle to the laboratory of Armed Forces Institute of Pathology for blood complete analysis by hematology analyzer machine. Data analysis was done using SPSS version 22. Results: In this study mean age was 40 ± 10.40 years. 54% patients were male and 46% patients were female. Mean platelet volume in patients presenting with psoriasis was 9.10fL with SD ± 2.12. Conclusion: Our study concludes that the mean platelet volume in patients presenting with psoriasis was 9.10fL with SD ± 2.12 which is in the normal range. Therefore, mean platelet volume is not affected by psoriasis. Key words: Mean platelet volume, psoriasis, severity, cross-sectional study
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