Silver nanoparticles embedded graphene oxide (Ag-GO) nanocomposite was prepared by one pot synthesis technique. The pristine composite was analyzed via FESEM, TEM, EDX, XPS and Raman spectroscopy. The nanocomposite exhibits enhanced photocatalytic and antibacterial activities with improved biocompatibility. Owing to synergy, Ag-GO composite inhibits growth and multiplication of the tested bacteria, Escherichia coli and Methicillin-resistant Staphylococcus aureus, in the first 2 h and then ceases their growth completely up to 24 h. The cell viability was found to be ∼ 85% for Ag-GO doses up to 160 ppm tested with human corneal epithelial cells, which indicates the nontoxic behavior of the composite. Moreover, Ag-GO nanocomposite exibits enhanced photocatalytic degradation properties for toxic organic dyes. The composite shows 98% degradation of rhodamine B in 24 min, 97% of methylene blue in 14 min and 99% of commercial dye-AY in 12 min. The photocatalytic efficiency was found to be about five times higher than that of the pure GO. During the photocatalytic process the reactive oxygen species (ROS) generated via surface plasmon resonance of Ag nanoparticles are responsible for the good bacterial population control as well as for the enhanced photocatalytic degradation activity. The reusability and recyclability of Ag-GO nanocomposite suggest its commercial utilization with structural stability and good biocompatibility.
A highly sensitive Au–GO hybrid nanostructure based non-enzymatic glucose biosensor is fabricated and exhibits superior sensitivity of 84.53 μA mM−1 cm−2. The biosensor also has applications for the detection of glucose in human blood serum, food samples and drinks.
The development of a highly sensitive and selective electrocatalyst for the detection of diclofenac sodium (D.S.) has remained a great challenge. In this work, graphene oxide functionalized with silver nanoparticles and zinc oxide (Ag–ZnO–GO) electrocatalyst was developed and investigated for the detection of D.S. The Ag–ZnO–GO/glassy carbon electrode exhibits high sensitivity and fast response within 3[Formula: see text]s owing to the efficient oxidation of D.S. at a very low potential at 0.25[Formula: see text]V. Moreover, the electrode shows a low detection limit of 0.02[Formula: see text][Formula: see text]M ([Formula: see text]) and long-term stability. To explore the synergic effects, the measurements of D.S. using GO, ZnO and ZnO–GO modified electrodes were also performed. The results demonstrate that the Ag–ZnO–GO nanocomposite electrode exhibits enhanced sensitivity and selectivity compared to the other electrodes. In addition, the electrode reveals excellent results for D.S. detection in the real samples as well. The enhanced performance of the proposed electrode is attributed to the improved electron transfer ability and synergic effects of the plasmonic Ag NPs and ZnO–GO structure. It is expected that Ag–ZnO–GO composite is a promising candidate for the construction of cost-effective electrochemical biosensors for medical and industrial applications.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.