In spite of ample researches and admirable achievements, still there is a reasonable amount of deaths happening every year due to cancer. Further, the number of new cases recorded are also not considerably reduced despite the advent of various preventive measures. Though current clinical approaches yield commendable results, it elicits dreadful systemic side-effects and also fails to avoid the recurrence of the disease. To address these issues, nanotechnology empowered modern drug delivery systems express fruitful properties for targeting and controlled delivery of biomolecules over a period of time. In the past decade, material based cancer research field has witnessed the exploration of several captivating drug delivery approaches for administration synthetic drug to genetic materials. Among those, the electrospinning based nanofibrous mesh has attracted several works on treating common dreadful cancers like lung, breast and colon respectively. The capability of nanofibers to enable increased drug loading, maintaining significant bioactivity, excellent drug encapsulation, controlled and targeted delivery has helped the researchers to achieve the successful administration of a variety of anti-cancer agents. This review gives an insight about the process of electrospinning, its essential parameters, types of drug incorporation and the works reported on common dreadful cancers. Moreover, the future direction of this effective alternative is also delineated, making electrospun nanofibers as a suitable vehicle for delivering drugs to the cancer sites.

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A series of bio-based photocrosslinked polyester membranes, poly(1,8-octanediol-itaconate-citrate-dodecandioate), (POSCI) were synthesized through polycondensation followed by photocrosslinking under UV irradiation in the presence of 2,2-dimethoxy-2-phenylacetophenone (DMPA) as photoinitiator (PI). Upon varied UV exposure time and DMPA content, the corresponding changes in chemical, structural, and mechanical properties of the polymer were studied. The transmission peak of FTIR spectrum centred at 1725 cm-1 indicates the formation of ester structure. Contact angle results suggested all of the synthesized POSCI membranes had hydrophilic properties as their contact angle is less than 90 °.  Sol-gel analysis shows that the swelling ratio of POSCI decreases while the gel fraction increases with increasing in photocrosslinking time. The tensile strength of POSCI, thus, increased correspondingly with longer UV exposure. Excess DMPA, however, proved otherwise.