Aim: Our study aimed to evaluate patient satisfaction 12 weeks after total knee arthroplasty (TKA) and determine preoperative and postoperative factors which influence short term patient satisfaction following TKA. Material and Method: Patients who underwent 40 primary TKAs were included. Patients were assessed by using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Short Form-36 (SF36), Visual Analog Scale (VAS)-pain, 50-meter walking test preoperatively and 12 weeks after TKA. The duration of walking was measured while the patients walked 50 m. Both pre and postoperative flexion and extension range of motion (ROM) of the knee were recorded. Postoperatively patient satisfaction was evaluated. Results: Preoperatively, there was no difference between satisfied and dissatisfied patients in terms of age, VAS-pain, SF36 sub scores, WOMAC sub scores, active and passive flexion and extension ROMs (p>0.05). Postoperatively, VAS-pain and SF36 general health and physical-emotional sub scores were lower and passive knee flexion was higher in satisfied patient group (p<0.05). Among clinical parameters, only postoperative VASpain had a significant negative impact on patient satisfaction (p<0.05). Other parameters including age, gender, pre and postoperative active flexion and extension ROMs, preoperative VASpain, WOMAC and 50-metre walking duration had no impact on patient satisfaction (p>0.05). Conclusion: Preoperative pain, disability and quality of life had no effect on postoperative short term patient satisfaction. Postoperative pain severity, knee flexion ROM degree and deterioration in quality of life had significant negative impact on postoperative patient satisfaction. Larger studies are necessary to further clarify the factors associated with dissatisfaction following TKA.
Revision surgery is required after total knee arthroplasty in some cases. Herein, we have presented a case who underwent total knee arthroplasty surgery 6 months ago and two-stage revision surgerydue to periprosthetic infection. Situations that require revision surgery have been discussed via our case.
Objectives:We aimed to determine thiol-disulphide homeostasis, which plays a vital role and to investigate the relationship among homeostatic parameters and disease. Methods: In this prospective study, we enrolled 38 patients with osteoarthritis (31 females and 7 males) and 38 healthy controls (30 females, 8 males volunteers). Diagnosis of osteoarthritis was made according to the American College of Rheumatology Criteria. The severity of osteoarthritis was assessed and classified according to the Kellgren-Lawrence grading scale. Results: The mean age was 63.8 (range; 53-74) years in the osteoarthritis group and 65.6 (range; 55-75) years in the control group. There were no significant differences between the patients and controls in respect to age, gender and body mass index (p > 0.05). Serum albumin (p = 0.605) and total protein levels (p = 0.605) between patients and controls were similar. In the osteoarthritis group disulphide/ native thiol percent ratios and disulphide/ total thiol percent ratios were found to be statistically higher (p = 0.002 and p = 0.002; respectively) and native/ total thiol percent ratios were significantly lower than that of the control group (p = 0.002). Conclusions: Thiol-disulphide homeostasis is weakened in osteoarthritis, and the balance shifts to the disulphide bond formation side. Substitution of thiol deficiency and correction of thioldisulphide imbalance may be beneficial in the managing treatment of the disease. Further studies may be needed for evaluating articular fluid thiol-disulphide homeostasis.
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