Therefore we are hopeful that our work will light a new insight into the screening of in vivo free radical scavenging model for evaluating anti-inflammatory compounds.
Cocos nucifera L. (family: arecaceae) is generally straight unbranched plant, traditionally cultivated for its fruit (coconut) in home gardens. In the present study, anti-inflammatory and antinociceptive (analgesic) activity of hydromethanol extract of Cocos nucifera L. (HECN) was evaluated in animal models. HECN showed significant (p < 0.05) and dosedependent anti-inflammatory activity in carrageenan induced paw oedema models of inflammation and the result was comparable with the standard drug diclofenac. In addition, the extract also showed highly significant (p < 0.01) antinociceptive activity. HECN treated group showed increase in the reaction time in hot plate method and decrease the writhing induced by acetic acid in mice when compared with control group animal. The anti-inflammatory and antinociceptive activity observed in the present study could be attributed largely to the presence of its antioxidant phytoconstituents such as flavonoid, saponin and polyphenols.
A significant part of cost of machining is associated with non-optimum use of cutting tool. Moreover cutting tool failure is responsible for almost 20% of the machining downtime. Thus, having knowledge of residual life of cutting tool is highly recommended so as to maximise the availability time and reduce the machining cost. The aim of this work is to find out residual life of a worn cutting tool which has been used for turning of Ti-6Al-4V alloy under constant cutting condition. The lognormal distribution is used to model the cutting tool life data. Remaining useful life of cutting tool is estimated using Mean Remaining Life (MRL) function. The results obtained from model are compared with the experimental results and it shows good agreement.
The study of the nature of knowledge and philosophical traditions is the foundation of the ancient Indian education system, which aims to enable human life not only to improve personal economic conditions, but also to improve the social, moral, and spiritual aspects of life. People are not only concerned about improving human life, but also realizing the “higher truth” from darkness to light, that is, “Tamaso Ma Jyotirgamaya”. Therefore, education is not only a means of making money but also contributes to the development of mankind along with enriching society. Therefore, our Indian sages or masters are committed to understanding the super-smart world and the use of spiritual power and adjusting their lives accordingly. The ultimate goal of education appears in Chitti Vrittinirodha (controlling spiritual activities related to the so-called materialist world). Therefore, education is an important means to make people’s potential development in a positive direction so that people can live in a society full of dignity. In the latest “National Education Policy-2020 (NEP-2020)” issued by the Indian government, many suggestions are made to integrate the current education system into the ancient education system. The rich heritage of ancient and eternal Indian knowledge and thought has always been the guiding principle of this policy. In Indian thought and philosophy, the pursuit of knowledge (Jnan), wisdom (Pragyaa), and truth (Satya) have always been regarded as the highest of mankind.
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