Erythema ab igne, also known as toasted skin syndrome, is an acquired asymmetric hyperpigmented dermatosis that is caused by repeated exposure to moderate heat or infrared radiation. Hyperpigmentation is caused by the degeneration of elastic fibers and basal cells resulting in the release of melanin. Historically found in bakers and industrial workers, this condition has recently resurfaced in medical literature with the use of novel heat sources such as laptops and heated car seats. While this condition can resolve spontaneously after removal of heat exposure, delay in diagnosis and persistent exposure can lead to permanent pigmentation or progression to Merkel cell carcinoma, basal cell carcinoma, and squamous cell carcinoma.
Hypophosphatemia is a rarely reported side-effect of cannabis use. The potential mechanisms of hypophosphatemia include enteric malabsorption/loss, excessive urinary excretion, or rapid trans-cellular shifts. Severe hypophosphatemia from daily marijuana use is a rare side-effect. A trans-cellular shift is the most likely proposed mechanism. Although it tends to self-correct fairly rapidly, close observation for the dreaded consequences related to hypophosphatemia is required. Both the users and providers must be aware of this rare association of hypophosphatemia with daily marijuana use.
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