By utilizing 2D speckle tracking cardiac echo, the current study aim is to assess any changes on the structureor function of heart muscle in previously healthy subjects with newly diagnosed subclinical hypothyroidism. Patients & methods: Forty consecutive symptomless patients with recently diagnosed untreated subclinical hypothyroidism who were attending our personal clinics and 40 age & sex matched healthy volunteers were randomly chosen (control group) registered within the study. All the patients in the current study were examined by standard 2D cardiac echo and speckle tracking echocardiography.The LV GLS and circumferential strain shown to be considerably lower in the patient's group in comparison with the healthy subjects. Left ventricular systolic function derived from Speckle tracking echocardiography was impaired in patients with subclinical hypothyroidism in comparison with healthy subjects.
Objective: Ankylosing spondylitis is a part of diseases called “seronegative spondyloarthropathy”. Affects the vertebral column, sacroiliac joint and peripheral joints. This chronic rheumatic disorder involved extra -articular parts like Heart, lungs, central nervous system and eyes. Ankylosing spondylitis lead to multiple cardiac complication such as systolic and diastolic dysfunction of left ventricle, valvular involvement , inflammation of aorta and pericardium with enlargement of the heart. Aim of the study: To evaluate of systolic and diastolic left ventricle dysfunction by echocardiography with speckle tracking in ankylosing spondylitis patients. Method: Fifty adult patients with Ankylosing Spondylitis fulfilling the inclusion criteria coming to outpatients of Merjan Medical City were recruited, diagnosed according to the criteria of the American College of Rheumatology criteria; 2D Echocardiography, Tissue Doppler Imaging and Speckle Tracking Echocardiography was done. Statistical analysis of correlation was done with Chi‑square test and t-test, the statistical significance was taken P < 0.05. Results :There was a significant lowering in the mean of global longitudinal strain in ankylosing spondylitis patients than in control ( p = 0.047*).
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