High-density lipoprotein (HDL) metabolism was studied in eight sedentary men before and after 14 and 32-48 weeks of exercise training. Subjects rode stationary bicycles 1 hour daily, 5 days each week for 14 weeks (n = 8), and 4 days each week thereafter for a total of 32-48 weeks (n = 7) of training. HDL metabolism was assessed with "1I-radiolabeled autologous HDL while subjects consumed defined diets. Maximal oxygen uptake increased 26± 7% (p
In brief The effects of resistance exercise and anabolic steroids on lipoprotein profiles were examined in female weight lifters. Steroid users had significantly depressed levels of HDL-C, HDI-2-C (p <.05), and apolipoprotein (apo) A-I compared with nonusers and controls. Nonusers had significantly higher levels of HDL-C and HDL2-C than the controls. Users had significantly less favorable ratios of total cholesterol (TC) to HDL-C, HDL2-C to HDL3-C, and apo A-I to apo B than nonusers or controls. Women who participate in resistance training apparently have significantly better lipoprotein profiles than their sedentary counterparts, but these changes do not offset the deleterious effects of steroid use.
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