Background: Hypertensive disorders are the most important cause of maternal and perinatal morbidity and mortality. The aim of present study is to know the changes in certain parameters of coagulation profile in pregnancy induced hypertensive patients in third trimester of pregnancy, so that treatment can be planned to reduce maternal morbidity and mortality. Methods: The study was undertaken at
AIM:In India, especially in rural population multiple factors adversely affect the incidence of premature rupture of membrane. The purpose of this study is to test the amniotic fluid Alpha feto protein as a reliable marker for the detection of PPROM and to test its efficacy for the purpose in the rural India. STUDY DESIGN: This study was conducted in the Department of Obstetrics & Gynecology, NIMS Medical College & Hospital, Jaipur, Rajasthan. This was a cross sectional study during period of one year with sample size of 100 patients. METHODS: Patients who were at ≥24 weeks of gestation with the complains of leaking per vaginum. Sample for Alphafetoprotein (AFP) estimation was collected by instilling 5 ml of distilled water into vagina, irrespective of pooling of amniotic fluid and sent to the biochemistry lab for the analysis and for the estimation of alpha fetoprotein by using Electroluminescence enzyme immunoassay method. RESULT: The sensitivity, specificity, positive predictive value and negative predictive value are 92%, 98%, 92% and 98% respectively. CONCLUSION: The AFP can be used as reliable marker to avoid unnecessary obstretic interventions for diagnosis of PROM.
Introduction: Triple-vessel Doppler flow velocity waveforms are widely used in obstetric practice. It has been studied for predicting a variety of adverse fetal outcomes. This is a descriptive type of observational study aimed to assess the role of umbilical artery (UA), middle cerebral artery (MCA), and uterine artery Doppler in pregnancy-induced hypertension (PIH) patients and their perinatal outcome.
Materials and methods:This study was conducted on 200 pregnant women (100 cases and 100 control) attending antenatal clinic after the assessment of inclusion and exclusion criteria over a period of 1 year. After an informed consent, 100 women with period of gestation >30 weeks diagnosed as PIH were subjected to transabdominal ultrasound during which triple-vessel Doppler waveforms were taken. Those patients with abnormal report underwent repeat Doppler and were observed for any changes indicating adverse fetal outcomes.Results: Out of 100 cases studied, 71 showed positive Doppler indices in any of the three vessels studied. The remaining 29 cases showed normal Doppler indices in all the three vessels studied. Among abnormal 71 cases, 56, 52, and 39 cases had abnormal MCA, uterine artery, and UA Doppler indices respectively. The specificity and the positive predictive value (PPV) of UA pulsatility index (PI) was more, as compared with the specificity and PPV of MCA PI and also cerebroplacental ratio.
Conclusion:Triple-vessel Doppler study is a safe, noninvasive technique, easy to perform, easy to interpret, and hence, most valuable tool in the management of high-risk pregnancy. Thus, it is very useful in predicting adverse perinatal outcome in PIH pregnancies.
Aim: This study is aimed to evaluate and validate the qualitative human chorionic gonadotropin β subunit (β-hCG) test of the vaginal uid
washings of pregnant women with premature rupture of fetal membranes (PROM). Materials & Methodology: A total of 60 pregnant women
between 26- and 36-weeks' gestation had participated in this study. The patients with leaking from the vagina were designated Group A, the patients
with no leaking from the vagina were Group B. After administering 5 cc of normal saline to posterior fornix by sterile injector, a total of 5 cc
washing uid was collected. human chorionic gonadotropin were examined on the same day on collected uid and both groups were compared
statistically. Result: In the current study 53.4% patients in group 1 and 60.0% patients from control group were between 19-25 years of age group.
Majority of patients were unbooked in both groups. 46.6% patients in PROM group and 56.6% patients in control group presents before 34 weeks
of gestation. There is no statistical signicance between two groups in terms of demographic data. Beta -HCG values in vaginal uid of Group 1
was signicantly higher than values in Group 2 with cut off value of Beta -HCG as 50mIU/dL. 83.4% patients from Group 1 (PROM Group) shows
Beta -HCG value more than 50Miu/dL.
Incidence of mecoium stained amniotic Fluid ranges from 7-22% and is an alarming sign of fetal compromise. It is associated with poor perinatal
outcome. Intrapartum amnioinfusion has been a method to reduce the risk of mecoium aspiration. Aims and Objectives: To determine the fetal
outcome in meconium stained liquor. Material and methods: This is a Prospective Case Control Study which was conducted in Department of
Obstetrics and Gynaecology, National Institute of Medical Sciences and Research, Jaipur in the study period of 18 months. A total of 242 patients
were included in the study and Were randomly divided into 2 groups and were compared for fetal outcome. Results: Amnioinfusion group(study
group) had higher incidence of vaginal delivery and better neonatal outcome. Conclusion: Intrapartum amnioinfusion decreases rate of caesarean
section and meconium aspiration syndrome.
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