Abrikossoff’s tumor, also known as granular cell tumor, is a rare tumor first described on the tongue by Ivanovich Abrikossoff in 1926. It is mainly located in the head and neck regions with preferential mucosal involvement and may occur at any age and in both sexes, although with a female predominance. Herein, we report two cases: the case of a nodule under the left breast in a 47-year-old female with a history of breast cancer and of a subcutaneous lesion on the right thigh in a 46-year-old female. The diagnosis of granular cell tumor was reached by biopsy with immunohistochemical staining, then treatment was completed by a large surgical excision. Key words: Abrikossoff; Skin; Granular cell tumor
Acute generalized exanthematous pustulosis (AGEP) is the most common generalized pustular rash. It is a delayed immunological reaction involving cellular immunity and is characterized by the sudden, simultaneous onset of high fever and scarlatiniform sheet erythema, which, in several hours, is covered with numerous pustules with a lactescent content, non-follicular, sterile, predominant on the face, trunk, and folds. It regresses in less than fifteen days after stopping the causative agent giving way to diffuse desquamation. Several incriminating factors in the triggering of this reaction, in particular, at the top of the list, taking medication, a viral (enterovirus) or bacterial (streptococcal) infection, yet its occurrence following an insect bite has been exceptionally reported in the literature. The diagnosis is established according to clinical and histological criteria. Herein, we report the case of a young Moroccan female with generalized AGEP related to insect bites. Key words: Acute Generalized Exanthematous Pustulosis; EuroSCAR; Insect Bites
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