Background: Esophageal cancer is of major concern worldwide, ranking sixth as the most common cause of cancer mortality. Lifestyles such as cigarette smoking, alcohol consumption, and poor dietary habits have been suggested to be associated with the carcinogenesis of esophageal cancer. Objectives: This study aimed to determine the factors affecting and associated with esophageal cancer in Khorramabad city from 2012 to 2014. Patients and Methods: This is an analytical study of 48 patients with esophageal cancer, including 80 controls. The patients were selected on the basis of a census. The data were collected using a questionnaire, and Chi-square, t-test, and one way ANOVA analyses were performed using SPSS 19. Results: In this study, 57.8% males and 42.2% females participated, while the mean age of the patients was 68.46 years old, and the mean age of the healthy individuals was 59.79 years old. The findings of this study showed a family history of cancer, anemia, and smoking, and associations with education, occupation, socioeconomic status, blood group, consumption of hot drinks, as well as a history of gastroesophageal reflux. In addition, there was a significant relationship, but no significant association, between alcohol consumption and esophageal cancer. Conclusions: According to the results of this study, the necessary measures to modify the risk factors, such as educational programs and changing food consumption patterns in the subjects, are effective, and can reduce the risk of esophageal cancer.
Background: COVID-19 is an emerging, highly contagious disease caused by the SARS-CoV-2 virus. Pregnant women appear to be at greater risk for COVID-19 infection and complications. Considering the importance of maternal and fetal healthcare, this study aims to evaluate some of the maternal, fetal, and neonatal outcomes in pregnant women with COVID-19. Methods: Pregnant women at the gestational age of 20 weeks or more were recruited and divided into two groups: cases (those with COVID-19 infection) and controls (those without the infection). Maternal complications during the current pregnancy, delivery factors, and fetal/neonatal complications were recorded and compared between the groups. Results: Maternal COVID-19 infection was highly associated with the need for emergency cesarean surgery (p=0.005), preterm labor (p=0.017), and the need for NICU admission for newborns (OR=0.05, p=0.000). Also, high rates of vertical transmission of the infection were observed in the cases. Conclusion: Maternal COVID-19 disease could be associated with a range of complications for both the mother and her newborn. The vertical transmission rate was also observed to be higher than previously reported in the literature. Further studies are required to evaluate this phenomenon.
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